Document Detail

Pulmonary hypertension and cor pulmonale.
MedLine Citation:
PMID:  8211354     Owner:  NLM     Status:  MEDLINE    
This article is directed primarily to primary care physicians. The challenge is to suspect, diagnose, and treat pulmonary arterial hypertension when treatment is most effective and before the effects of cor pulmonale become fully manifested. A good history and physical examination should be followed by electrocardiographic and roentgenographic evaluations. Of additional value are arterial blood gas measurements, two-dimensional echocardiography, first-pass radionuclide angiography, and catheterization of the right ventricle. Chronic obstructive pulmonary disease (COPD) is one of the more common etiologies of pulmonary hypertension and cor pulmonale. COPD is most common in the elderly and cor pulmonale is fairly common among those with COPD; therefore, hypoxic pulmonary hypertension and the resultant cor pulmonale occur mostly in older patients. Because early signs are nonspecific, diagnosis and treatment are often delayed until the pulmonary disorder is severe. Thus it is imperative that the primary care physician be cognizant of this serious problem. Standard treatment of left ventricular failure (ie, "congestive heart failure") could have adverse effects in patients with cor pulmonale.
H M Vandiviere
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Southern medical journal     Volume:  86     ISSN:  0038-4348     ISO Abbreviation:  South. Med. J.     Publication Date:  1993 Oct 
Date Detail:
Created Date:  1993-11-23     Completed Date:  1993-11-23     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0404522     Medline TA:  South Med J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  2S7-10     Citation Subset:  AIM; IM    
Department of Pediatrics, College of Medicine, University of Kentucky, Lexington 40436.
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MeSH Terms
Adrenal Cortex Hormones / therapeutic use
Age Factors
Blood Gas Analysis
Digitalis Glycosides / therapeutic use
Diuretics / therapeutic use
Family Practice / methods
Heart Catheterization
Heart Failure / etiology,  therapy
Hypertension, Pulmonary / blood,  diagnosis*,  epidemiology,  etiology,  therapy*
Lung Diseases, Obstructive / blood,  complications,  diagnosis*,  epidemiology,  therapy*
Magnetic Resonance Imaging
Medical History Taking
Oxygen Inhalation Therapy
Physical Examination
Pulmonary Heart Disease / blood,  diagnosis*,  epidemiology,  etiology,  therapy*
Referral and Consultation
Vasodilator Agents / therapeutic use
Ventricular Function, Left
Ventricular Function, Right
Ventriculography, First-Pass
Reg. No./Substance:
0/Adrenal Cortex Hormones; 0/Digitalis Glycosides; 0/Diuretics; 0/Vasodilator Agents

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