Document Detail

Pulmonary hypertension complicating hepatocellular carcinoma.
MedLine Citation:
PMID:  6090260     Owner:  NLM     Status:  MEDLINE    
A case of primary liver cell carcinoma is presented in which tumor emboli to the pulmonary microvasculature resulted in pulmonary hypertension, documented by clinical, radiologic, electrocardiographic, and cardiac catheter studies. Emboli arose from tumor invading the portal vein and passed via a patent splenorenal shunt to the systemic venous and pulmonary arterial microvasculature. Despite a prolonged clinical course (20 mo) there was no radiologic evidence of pulmonary metastases and, histologically, tumor emboli were seen to undergo organization and recanalization.
I R Willett; R C Sutherland; M F O'Rourke; F J Dudley
Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Gastroenterology     Volume:  87     ISSN:  0016-5085     ISO Abbreviation:  Gastroenterology     Publication Date:  1984 Nov 
Date Detail:
Created Date:  1984-11-09     Completed Date:  1984-11-09     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0374630     Medline TA:  Gastroenterology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1180-4     Citation Subset:  AIM; IM    
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MeSH Terms
Carcinoma, Hepatocellular / complications*,  pathology
Hypertension, Pulmonary / etiology*,  pathology
Liver Neoplasms / complications*,  pathology
Middle Aged
Neoplasm Invasiveness
Neoplastic Cells, Circulating*
Portal Vein / pathology
Splenorenal Shunt, Surgical

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