Document Detail

Pulmonary hypertension caused by medial hypertrophy associated with aortic stenosis and preductal coarctation.
MedLine Citation:
PMID:  9236374     Owner:  NLM     Status:  MEDLINE    
A 7-month-old female infant with aortic stenosis, preductal coarctation, and pulmonary hypertension underwent operation. Intraoperative lung biopsy revealed marked medial hypertrophy of the pulmonary arterioles. This histopathology is compatible with persistent pulmonary hypertension in the newborn. She is alive about 5 years after the operation, but pulmonary hypertension remains. The pathogenesis is discussed.
M Aota; S Nomoto; S Yamaki; T Ban
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  64     ISSN:  0003-4975     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  1997 Jul 
Date Detail:
Created Date:  1997-08-21     Completed Date:  1997-08-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  244-7     Citation Subset:  AIM; IM    
Department of Cardiovascular Surgery, Faculty of Medicine, Kyoto University, Japan.
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MeSH Terms
Aortic Coarctation / complications
Aortic Valve Stenosis / complications
Arterioles / pathology
Hypertension, Pulmonary / etiology*,  pathology
Infant, Newborn
Lung / blood supply*,  pathology
Persistent Fetal Circulation Syndrome

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