| Pulmonary hypertension and antiphospholipid antibody in a patient with Sjögren's syndrome. | |
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MedLine Citation:
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PMID: 7718958 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A 57-year-old female patient with Sjögren's syndrome was complicated with pulmonary hypertension (PH) and antiphospholipid antibody (aPL). She had a history of fetal losses, deep vein thrombosis and chronic thyroiditis. On admission, severe pulmonary hypertension, thrombocytopenia, lupus anticoagulant and a decreased level of protein C were found. Pulmonary artery perfusion scintigram revealed multiple defects. She died suddenly despite an intensive therapy. Intimal proliferation with angiomatoid lesions in small pulmonary arteries was observed by autopsy. Since a close relationship between PH and aPL in connective tissue disease is found, it is important to carefully analyze the antiphospholipid antibodies in patients with PH. |
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Authors:
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S Biyajima; T Osada; H Daidoji; T Hisaoka; Y Sakakibara; J Tajima; M Nakazawa; H Kuroda; S Kobayashi |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Internal medicine (Tokyo, Japan) Volume: 33 ISSN: 0918-2918 ISO Abbreviation: Intern. Med. Publication Date: 1994 Dec |
Date Detail:
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Created Date: 1995-05-25 Completed Date: 1995-05-25 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9204241 Medline TA: Intern Med Country: JAPAN |
Other Details:
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Languages: eng Pagination: 768-72 Citation Subset: IM |
Affiliation:
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Department of Medicine, Koutou Hospital, Tokyo. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antiphospholipid Syndrome
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complications*,
diagnosis Fatal Outcome Female Humans Hypertension, Pulmonary / complications*, diagnosis Middle Aged Pulmonary Embolism / complications, diagnosis Sjogren's Syndrome / complications*, diagnosis |
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