Document Detail


Pulmonary hyalinizing granuloma.
MedLine Citation:
PMID:  19727240     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To present clinical and pathologic features of pulmonary hyalnizing granuloma through analyzing three cases found in our institution and reviewing cases reported in the English language literature.
METHODS AND RESULTS: Three cases of pulmonary hyalnizing granuloma identified at our institution during the past ten years were reviewed. In the first case, the patient presented with concurrent pulmonary hyalinizing granuloma and histoplasmosis. In the second case, the patient presented with a 5.5 cm lung mass and a separate smaller lesion radiologically resembling bronchogenic carcinoma. There was very prominent polyclonal lymphocytic proliferation at the periphery especially of the smaller lesion likely representing an early stage of the disease process. In the third case, the patient presented with multiple subpleural plaque-like lesions in addition to nodular lesions of the lung. All cases also demonstrated various degrees of lymphocytic infiltration within the lesions. The English literature has been reviewed through searching the PubMed.
CONCLUSION: Since patients with pulmonary hyalinizing granuloma demonstrated a spectrum of clinical presentations, radiologic changes and histologic features with a variety of associated clinical disorders, pulmonary hyalnizing granuloma is more in keeping with a clinicopathologic entity rather than a specific pathologic disease.
Authors:
Zhao-lin Xu; Drew Bethune; Daria Manos; Annette Foyle; Harry Henteleff; Michael Johnston; Yannick Cartier
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences     Volume:  41     ISSN:  1671-167X     ISO Abbreviation:  Beijing Da Xue Xue Bao     Publication Date:  2009 Aug 
Date Detail:
Created Date:  2009-09-03     Completed Date:  2011-01-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101125284     Medline TA:  Beijing Da Xue Xue Bao     Country:  China    
Other Details:
Languages:  eng     Pagination:  463-8     Citation Subset:  IM    
Affiliation:
Department of Pathology, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, Nova Scotia, Canada B3H 1V8. zxu3@dal.ca
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MeSH Terms
Descriptor/Qualifier:
Adult
Diagnosis, Differential
Female
Granuloma, Respiratory Tract / pathology*,  radiography
Humans
Hyalin*
Lung Diseases / pathology*,  radiography
Male
Middle Aged
Tomography, X-Ray Computed

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