Document Detail


Pulmonary gas exchange is reduced by the cardiovascular diving response in resting humans.
MedLine Citation:
PMID:  18088568     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The diving response reduces the pulmonary O(2) uptake in exercising humans, but it has been debated whether this effect is present at rest. Therefore, respiratory and cardiovascular responses were recorded in 16 resting subjects, performing apnea in air and apnea with face immersion in cold water (10 degrees C). Duration of apneas were predetermined to be identical in both conditions (average: 145 s) and based on individual maximal capacity (average: 184 s). Compared to apnea in air, an augmented diving response was elicited by apnea with face immersion. The O(2) uptake from the lungs was reduced compared to the resting eupneic control (4.6 ml min(-1)kg(-1)), during apnea in air (3.6 ml min(-1)kg(-1)) and even more so during apnea with face immersion (3.4 ml min(-1)kg(-1)). We conclude that the cardiovascular adjustments of the diving response reduces pulmonary gas exchange in resting humans, allowing longer apneas by preserving the lungs' O(2) store for use by vital organs.
Authors:
Johan P A Andersson; Gustaf Biasoletto-Tjellström; Erika K A Schagatay
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Publication Detail:
Type:  Controlled Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't     Date:  2007-11-07
Journal Detail:
Title:  Respiratory physiology & neurobiology     Volume:  160     ISSN:  1569-9048     ISO Abbreviation:  Respir Physiol Neurobiol     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-02-25     Completed Date:  2008-06-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101140022     Medline TA:  Respir Physiol Neurobiol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  320-4     Citation Subset:  IM    
Affiliation:
Department of Cell and Organism Biology, Lund University, Lund, Sweden. Johan.Andersson@cob.lu.se
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Blood Pressure / physiology
Breath Tests / methods
Cardiovascular System*
Diving / physiology*
Electrocardiography / methods
Heart Rate / physiology
Humans
Immersion
Lactic Acid / blood
Male
Pulmonary Gas Exchange / physiology*
Rest / physiology*
Chemical
Reg. No./Substance:
50-21-5/Lactic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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