| Pulmonary functions in patients with diabetes mellitus. | |
| | |
MedLine Citation:
|
PMID: 21712938 Owner: NLM Status: PubMed-not-MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: A reduction in lung capacity has been reported previously among diabetics. According to WHO estimates, Pakistan is currently eighth in the prevalence of diabetes mellitus (DM) and will become fourth by the year 2025 with over 15 million individuals. This study was designed to see the impairment of lung functions on spirometry in DM patients. OBJECTIVE: Our aim was to investigate the pulmonary functions tests of Pakistani patients with DM. MATERIALS AND METHODS: Between January to July 2004, 128 subjects who were never-smokers and had no acute or chronic pulmonary disease were recruited. Sixty-four of these subjects had DM and 64 were healthy matched controls. All underwent screening with detailed history, anthropometry, lipid profile, and spirometric measurements at the Aga Khan University Hospital, Karachi, Pakistan. RESULTS: The mean age of diabetics and matched control were 54.3±9 and 54.0±8 (P<0.87) years, respectively. Diabetes patients showed a significant reduction in the forced vital capacity (FVC) [mean difference (95% CI) - 0.36 (-0.64, -0.07) P<0.01], forced expiratory volume in one second (FEV(1)) [- 0.25(-0.50, -0.003) P<0.04], and slow vital capacity (SVC) [- 0.28(-0.54, -0.01) P<0.04], relative to nondiabetic controls. There was no significant difference noted in the forced expiratory ratio and maximum mid-expiratory flow between the groups. There was also a significant higher level of triglycerides noted among diabetics (P<0.001). CONCLUSION: Diabetic patients showed impaired lung function independent of smoking. This reduced lung function is likely to be a chronic complication of diabetes mellitus. |
| | |
Authors:
|
Muhammad Irfan; Abdul Jabbar; Ahmed Suleman Haque; Safia Awan; Syed Fayyaz Hussain |
Related Documents
:
|
9177618 - Serum uric acid and insulin secretion in diabetes mellitus. 1563538 - Predictive value of testing random urine sample to detect microalbuminuria in diabetic ... 17409758 - Correlation between increased serum sfas levels and microalbuminuria in type 1 diabetic... 12227558 - Glomerular podocyte endocytosis of the diabetic rat. 11996958 - Coronary artery disease is associated with the ratio of apolipoprotein a-i/b and serum ... 2847588 - Determination of glucose-6-phosphatase activity using the glucose dehydrogenase-coupled... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Lung India : official organ of Indian Chest Society Volume: 28 ISSN: 0974-598X ISO Abbreviation: Lung India Publication Date: 2011 Apr |
Date Detail:
|
Created Date: 2011-06-29 Completed Date: 2011-07-14 Revised Date: 2011-08-01 |
Medline Journal Info:
|
Nlm Unique ID: 8405380 Medline TA: Lung India Country: India |
Other Details:
|
Languages: eng Pagination: 89-92 Citation Subset: - |
Affiliation:
|
Department of Medicine, The Aga Khan University Hospital, Karachi, Pakistan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Ethics in writing: Learning to stay away from plagiarism and scientific misconduct.
Next Document: Clinical and laboratory profile of patients with TB/HIV coinfection: A case series of 50 patients.