| Pulmonary function changes in children after transcatheter closure of atrial septal defect. | |
| | |
MedLine Citation:
|
PMID: 19768807 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
This study was performed to assess changes in pulmonary function test (PFT) and pulmonary outcome after transcatheter closure of atrial septal defect (ASD) in pediatric patients. A total 55 pediatric patients undergoing transcatheter ASD closure received PFT at baseline (day before ASD closure), and at 3 days and 6 months after procedure. Forced vital capacity (FVC), forced expired volume in 1 sec (FEV(1)), FEV(1) to FVC ratio (FEV(1)/FVC), peak expiratory flow (PEF), and mean forced expiratory flow during the middle half of FVC (FEF(25-75)) were measured. Individually, subjects were classified by spirometry as normal, obstructive or restrictive, to evaluate the effect of transcatheter closure on pulmonary outcome. These 55 children had significantly reduced mean PEF and FEF(25-75) (84 +/- 24%, P = 0.040 and 76 +/- 22%, P = 0.010, respectively) at baseline, with FEF(25-75) reduced significantly at 3 days and 6 months (78 +/- 24%, P = 0.010 and 81 +/- 24%, P = 0.040, respectively) after transcatheter closure. Six months after transcatheter closure of ASD, significant improvement was observed in mean FVC (94 +/- 19% vs. 98 +/- 15%, P = 0.034) and FEV(1) (90 +/- 20% vs. 96 +/- 19%, P = 0.008). Assessed individually, better pulmonary outcome was found in patients without pulmonary hypertension (PH) (chi(2) = 8.333, P = 0.044). PFT disturbance was observed in significant flow limitation in the peripheral airway of ASD patients. Improved PFT was found after transcatheter closure and better pulmonary outcome was observed in patients without PH. ASD children need monitoring pulmonary function and should receive transcatheter closure before PH develops. |
| | |
Authors:
|
Yu-Sheng Lee; Mei-Jy Jeng; Pei-Chen Tsao; Chia-Feng Yang; Wen-Jue Soong; Betau Hwang; Ran-Bin Tang |
Related Documents
:
|
7572627 - Improvement in noninvasive electrophysiologic findings in children after transcatheter ... 22065107 - Impact of fat obesity on laparoscopic total mesorectal excision: more reliable indicato... 6838267 - Short-term variations of the right ventricular/left ventricular pressure ratio followin... 10424997 - Reoperation in adults with repair of tetralogy of fallot: indications and outcomes. 23684157 - Patient-prosthesis mismatch and reduction in left ventricular mass after aortic valve r... 10604347 - Modified seromuscular tube: serosa lined bowel wall imbrication as a continent outlet f... |
Publication Detail:
|
Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Pediatric pulmonology Volume: 44 ISSN: 1099-0496 ISO Abbreviation: Pediatr. Pulmonol. Publication Date: 2009 Oct |
Date Detail:
|
Created Date: 2009-09-30 Completed Date: 2010-02-17 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8510590 Medline TA: Pediatr Pulmonol Country: United States |
Other Details:
|
Languages: eng Pagination: 1025-32 Citation Subset: IM |
Affiliation:
|
Department of Pediatrics, Taipei Veterans General Hospital, Taipei, Taiwan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Analysis of Variance Cardiac Surgical Procedures / adverse effects*, methods Child Female Follow-Up Studies Forced Expiratory Volume Heart Catheterization Heart Septal Defects, Atrial / complications, diagnosis, surgery* Humans Hypertension, Pulmonary / diagnosis*, etiology Male Postoperative Care Postoperative Complications / diagnosis Preoperative Care Probability Prospective Studies Respiratory Function Tests Respiratory Insufficiency / etiology*, physiopathology Risk Assessment Surgical Procedures, Minimally Invasive / adverse effects, methods Time Factors Vital Capacity |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Healthcare expenditures for privately insured people with cystic fibrosis.
Next Document: Controllable protein cleavages through intein fragment complementation.