Document Detail

Pulmonary function changes after large volume paracentesis.
MedLine Citation:
PMID:  8503387     Owner:  NLM     Status:  MEDLINE    
Large volume paracentesis (LVP) is a safe, rapid, and effective treatment of ascites in cirrhotic patients. We investigated the effects of a 5-L aspiration of ascites on pulmonary function parameters in eight hemodynamically stable patients with cirrhosis and tense ascites. None had known lung disease or abnormal chest roentgenograms. At baseline, mean lung volumes, diffusing capacity, and arterial pO2 were all reduced from normal predicted values. Airflow, however, when related to lung volume, was normal. Post-LVP, lung volumes increased significantly; the mean expiratory reserve volume showed the greatest percent increase (105%) and correlated with the increases in the vital capacity, functional residual capacity, and total lung capacity. Airflow, the mean diffusing capacity, and arterial oxygenation were not significantly changed after LVP. We conclude that LVP significantly increases indices of lung volume but does not significantly alter parameters of airflow or gas exchange.
K A Berkowitz; M S Butensky; R L Smith
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of gastroenterology     Volume:  88     ISSN:  0002-9270     ISO Abbreviation:  Am. J. Gastroenterol.     Publication Date:  1993 Jun 
Date Detail:
Created Date:  1993-07-01     Completed Date:  1993-07-01     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0421030     Medline TA:  Am J Gastroenterol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  905-7     Citation Subset:  IM    
New York Department of Veterans Affairs Medical Center, New York.
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MeSH Terms
Ascites / physiopathology,  therapy*
Drainage / methods
Liver Cirrhosis / complications*
Lung Volume Measurements*
Middle Aged
Pulmonary Gas Exchange / physiology*
Pulmonary Ventilation / physiology*

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