Document Detail


Pulmonary function and alpha-1-antitrypsin levels in patients after so-called idiopathic spontaneous pneumothorax.
MedLine Citation:
PMID:  3496137     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The subpleural blebs found in patients with so-called idiopathic spontaneous pneumothorax suggest that pneumothorax could possibly be an early manifestation of pulmonary emphysema in these subjects. In order to investigate this hypothesis, fifty-six young adults (32 +/- 9 yr; 45 men and 11 women) were examined after idiopathic spontaneous pneumothorax. All were apparently healthy with no history of pulmonary disease. Physical and X-ray examination were normal. The episode of pneumothorax was the only sign of lung pathology. A control group of 20 healthy people was also studied. The mean age and smoking habits in the patients and control groups were similar. Only four patients (7%) revealed definite evidence of emphysema, consisting of a reduction of diffusing capacity, decrease of lung recoil pressure and a secondary reduction of forced expiratory flow at 50% of vital capacity. Serum alpha-1-antitrypsin levels in these patients were normal.
Authors:
A Pawlowicz; W Droszcz
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Bulletin européen de physiopathologie respiratoire     Volume:  23     ISSN:  0395-3890     ISO Abbreviation:  Bull Eur Physiopathol Respir     Publication Date:    1987 Jan-Feb
Date Detail:
Created Date:  1987-08-05     Completed Date:  1987-08-05     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7605263     Medline TA:  Bull Eur Physiopathol Respir     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1-4     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Female
Humans
Lung / physiopathology*
Lung Compliance
Male
Middle Aged
Osmolar Concentration
Pneumothorax / blood,  physiopathology*
Reference Values
Respiratory Function Tests
alpha 1-Antitrypsin / blood*
Chemical
Reg. No./Substance:
0/alpha 1-Antitrypsin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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