Document Detail

Pulmonary excretion rates of carbon monoxide using a modified technique: differences between premature and full-term infants.
MedLine Citation:
PMID:  7104416     Owner:  NLM     Status:  MEDLINE    
The pathophysiology of the exaggerated hyperbilirubinemia in premature infants remains unclear. The relative contribution of bilirubin production may be estimated by measuring the pulmonary excretion rate of carbon monoxide (VeCO). We found that the mean VeCO of premature infants, 16.7 +/- 5.0 microliters/kg/h, was significantly elevated (p less than 0.05) compared with the mean VeCO of full-term infants, 13.9 +/- 3.5 microliters/kg/h. Premature infants who required phototherapy had a significantly (p less than 0.05) higher mean VeCO than those who did not. The VeCO did not correlate with gestational age, implying that factors which associate frequently but variably with gestational age may have an important influence on heme catabolism.
R S Cohen; C R Ostrander; B E Cowan; G B Stevens; A O Hopper; D K Stevenson
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Biology of the neonate     Volume:  41     ISSN:  0006-3126     ISO Abbreviation:  Biol. Neonate     Publication Date:  1982  
Date Detail:
Created Date:  1982-10-29     Completed Date:  1982-10-29     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0247551     Medline TA:  Biol Neonate     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  289-93     Citation Subset:  IM    
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MeSH Terms
Carbon Monoxide / analysis*
Infant, Newborn
Infant, Premature*
Jaundice, Neonatal / physiopathology*
Lung / physiopathology*
Grant Support
Reg. No./Substance:
630-08-0/Carbon Monoxide

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