Document Detail


Pulmonary embolization of microcrystalline cellulose in a lung transplant recipient.
MedLine Citation:
PMID:  15896764     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Intravenous injection of drugs that contain insoluble foreign material can lead to pulmonary embolization of the material and can have devastating results, including pulmonary hypertension and death. Most cases are detected after the onset of extensive, irreversible damage, precluding potentially life-saving intervention, or are detected at autopsy. We report here a case of microcrystalline cellulose embolization in a lung transplant recipient detected at routine transbronchial biopsy, and we describe the circumstances associated with the development of this condition and its clinical outcome.
Authors:
Timothy A Fields; Shannon J McCall; B Diane Reams; Victor L Roggli; Scott M Palmer; David N Howell
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation     Volume:  24     ISSN:  1053-2498     ISO Abbreviation:  J. Heart Lung Transplant.     Publication Date:  2005 May 
Date Detail:
Created Date:  2005-05-17     Completed Date:  2005-09-20     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  9102703     Medline TA:  J Heart Lung Transplant     Country:  United States    
Other Details:
Languages:  eng     Pagination:  624-7     Citation Subset:  IM    
Affiliation:
Department of Pathology, Duke University Medical Center, Durham, North Carolina 27710, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Biopsy
Cellulose / administration & dosage,  adverse effects*
Cystic Fibrosis / surgery
Excipients / administration & dosage,  adverse effects*
Female
Humans
Injections, Intravenous
Lung / pathology*
Lung Transplantation*
Pulmonary Embolism / chemically induced*,  pathology
Grant Support
ID/Acronym/Agency:
DK062833-02/DK/NIDDK NIH HHS
Chemical
Reg. No./Substance:
0/Excipients; 0/microcrystalline cellulose; 9004-34-6/Cellulose

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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