| Pulmonary embolism. | |
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MedLine Citation:
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PMID: 20628658 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Pulmonary embolism remains a common and potentially preventable cause of death. OBJECTIVE: This article reviews the epidemiology, clinical features, diagnostic process, and treatment of pulmonary embolism. DISCUSSION: Well recognised risk factors include recent hospitalisation, other causes of immobilisation, cancer, and oestrogen exposure. Diagnostic algorithms for pulmonary embolism that incorporate assessment of pretest probability and D-dimer testing have been developed to limit the need for diagnostic imaging. Anticoagulation should be administered promptly to all patients with pulmonary embolism with low molecular weight heparin being the initial anticoagulant of choice, although thrombolysis is indicated for patients presenting with haemodynamic compromise. Following initial anticoagulation warfarin therapy should be continued for a minimum of 3 months. Long term anticoagulation with warfarin should be considered in patients with unprovoked pulmonary embolism, due to an increased risk of recurrence after ceasing anticoagulation. The availability of new anticoagulants is likely to significantly impact on the treatment of patients with pulmonary embolism, although the exact role of these drugs is still to be defined. |
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Authors:
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Simon McRae |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Australian family physician Volume: 39 ISSN: 0300-8495 ISO Abbreviation: Aust Fam Physician Publication Date: 2010 Jul |
Date Detail:
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Created Date: 2010-07-14 Completed Date: 2011-03-07 Revised Date: 2012-09-18 |
Medline Journal Info:
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Nlm Unique ID: 0326701 Medline TA: Aust Fam Physician Country: Australia |
Other Details:
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Languages: eng Pagination: 462-6 Citation Subset: IM |
Affiliation:
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Department of Haematology, South Australia Pathology, Royal Adelaide Hospital, South Australia. simon.mcrae@health.sa.gov.au |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Algorithms Anticoagulants / therapeutic use Antifibrinolytic Agents / therapeutic use Australia Fibrin / metabolism Fibrin Fibrinogen Degradation Products / analysis Fibrinolytic Agents / therapeutic use Heparin, Low-Molecular-Weight / therapeutic use Humans Pulmonary Embolism / diagnosis*, drug therapy, etiology Risk Assessment Risk Factors Venous Thromboembolism / diagnosis*, drug therapy, etiology |
| Chemical | |
Reg. No./Substance:
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0/Anticoagulants; 0/Antifibrinolytic Agents; 0/Fibrin Fibrinogen Degradation Products; 0/Fibrinolytic Agents; 0/Heparin, Low-Molecular-Weight; 0/fibrin fragment D; 9001-31-4/Fibrin |
| Comments/Corrections | |
Comment In:
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Aust Fam Physician. 2011 Jan-Feb;40(1-2):9-10; author reply 10
[PMID:
21394938
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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