Document Detail

Pulmonary embolism in younger adults.
MedLine Citation:
PMID:  1600765     Owner:  NLM     Status:  MEDLINE    
To test the hypothesis that the clinical presentation and outcomes are different when pulmonary embolism occurs in younger (age 18 to 40 years) as compared to older (age greater than 40 years) adults, 40 younger patients were compared with older patients. No risk factors could be identified in 28 percent of the younger group. Normal physical examinations were more common (58 vs 28 percent, p = 0.01) among younger as compared with older adults. Hypoxemia was absent in 29 percent of the younger and 3 percent of the older group (p = 0.004); P(A-a)O2 was significantly lower among younger patients even after controlling for age. Mortality was decreased sevenfold (2.5 vs 18 percent, p = 0.03) among younger patients. These data indicate that pulmonary embolism tends to have a subtle presentation in younger adults. When diagnosed and treated, the mortality rate is substantially less among younger as compared with older patients.
R M Green; T J Meyer; M Dunn; J Glassroth
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Chest     Volume:  101     ISSN:  0012-3692     ISO Abbreviation:  Chest     Publication Date:  1992 Jun 
Date Detail:
Created Date:  1992-07-15     Completed Date:  1992-07-15     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0231335     Medline TA:  Chest     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1507-11     Citation Subset:  AIM; IM    
Department of Medicine, Northwestern Memorial Hospital, Chicago.
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MeSH Terms
Aged, 80 and over
Chicago / epidemiology
Middle Aged
Pulmonary Embolism / diagnosis,  epidemiology*,  mortality
Regression Analysis
Retrospective Studies
Risk Factors

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