| Pulmonary embolism as a cause of a reduced performance capacity of endurance trained men - report of 2 cases | |
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MedLine Citation:
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PMID: 20717863 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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HISTORY AND ADMISSION FINDINGS: Two trained long-distance runners, aged 53 and 58 years, respectively, presented (independently) at our outpatient department because of an acute reduction in physical performance after considerable exertion. Neither had specific clinical symptoms, particularly no dyspnea. INVESTIGATIONS: Neither patient had abnormal findings on physical examination, such as signs for deep venous thrombosis. The electrocardiogram and echocardiography were normal. Exercise tests revealed a significant limitation in physical performance and, in one patient, a reduction in arterial blood oxygen and elevated d-dimers as the only abnormal laboratory test result. DIAGNOSIS, TREATMENT AND COURSE: The diagnosis of pulmonary embolism was made by computed tomography, which showed the typical changes. In both patients venous phlebography revealed deep vein thrombosis and signs of post-thrombotic changes. Laboratory tests were unremarkable, with normal blood coagulation and no factor II mutations. Anticoagulants were administered to each patient and they slowly resumed their training program. At a subsequent examination physical performance had improved, but there was still a reduction in arterial oxygen during exercise. CONCLUSION: Even endurance-trained sportspersons without thrombophilic risk factors may develop deep vein thrombosis. Even when there are no symptoms, pulmonary embolism should always be included in the differential diagnosis of a sudden and significant reduction in physical performance. |
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Authors:
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U Korsten-Reck; J Winterer; D König; Hans-Hermann Dickhuth |
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Publication Detail:
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Type: English Abstract; Journal Article Date: 2010-08-17 |
Journal Detail:
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Title: Deutsche medizinische Wochenschrift (1946) Volume: 135 ISSN: 1439-4413 ISO Abbreviation: Dtsch. Med. Wochenschr. Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-08-18 Completed Date: 2010-09-15 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0006723 Medline TA: Dtsch Med Wochenschr Country: Germany |
Other Details:
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Languages: ger Pagination: 1596-600 Citation Subset: IM |
Copyright Information:
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Georg Thieme Verlag KG Stuttgart * New York. |
Affiliation:
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Medizinische Klinik, Abt. Präventive und Rehabilitative Sportmedizin, Universität Freiburg, Freiburg. |
Vernacular Title:
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Lungenembolie als Ursache einer Leistungsminderung bei Ausdauersportlern - 2 Kasuistiken. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Angiography Anticoagulants / therapeutic use Athletic Performance / physiology* Diagnosis, Differential Electrocardiography Enoxaparin / therapeutic use Exercise Test Fibrin Fibrinogen Degradation Products / metabolism Follow-Up Studies Humans Male Middle Aged Oxygen / blood Phenprocoumon / therapeutic use Physical Endurance / physiology* Pulmonary Embolism / diagnosis*, drug therapy, physiopathology Running / physiology* Tomography, X-Ray Computed Venous Thrombosis / diagnosis, drug therapy, physiopathology |
| Chemical | |
Reg. No./Substance:
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0/Anticoagulants; 0/Enoxaparin; 0/Fibrin Fibrinogen Degradation Products; 0/fibrin fragment D; 435-97-2/Phenprocoumon; 7782-44-7/Oxygen |
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