Document Detail

Pulmonary effects of submerged oxygen breathing: 4-, 6-, and 8-hour dives at 140 kPa.
MedLine Citation:
PMID:  16457084     Owner:  NLM     Status:  MEDLINE    
Elevated inspired oxygen partial pressures (PO2) may cause pulmonary oxygen toxicity (PO2T). However, normal variability and water immersion also cause pulmonary function (PF) changes. In 21 subjects, we measured the variability of flow-volume parameters and diffusing capacity for carbon monoxide (DLCO) for six weeks without diving. In 24 divers, we compared the effects of air (P(I)O2 = 0.3 atm = 30 kPa) and oxygen (P(I)O2 = 1.4 atm = 140 kPa) during paired resting dives of 4, 6, or 8 hours in a freshwater pool 4.6 m deep. Without diving, median coefficients of variation (CV) were: vital capacity, 3.2%; FEV1, 3.5%; peak flow, 7.0%; and DLCO, 5.9%. Measurements within 2.4.CV of baseline were considered unchanged. After 4-, 6-, and 8- hour air dives, PF decreased in one, one, and four subjects, respectively, and three, one, and two, respectively, reported symptoms. After the oxygen dives, PF decreased in two, three, and four subjects, respectively, and two, four, and seven, respectively, reported symptoms. PO2T persisted for several days after 8-hour oxygen dives.
B E Shykoff
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc     Volume:  32     ISSN:  1066-2936     ISO Abbreviation:  Undersea Hyperb Med     Publication Date:    2005 Sep-Oct
Date Detail:
Created Date:  2006-02-06     Completed Date:  2006-02-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9312954     Medline TA:  Undersea Hyperb Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  351-61     Citation Subset:  IM; S    
Navy Experimental Diving Unit, Panama City, FL, USA.
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MeSH Terms
Analysis of Variance
Diving / physiology*
Lung / physiology*
Middle Aged
Oxygen / administration & dosage*
Partial Pressure
Peak Expiratory Flow Rate / physiology
Pulmonary Diffusing Capacity / physiology
Respiratory Function Tests
Time Factors
Vital Capacity / physiology*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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