Document Detail


Pulmonary diffusing capacity after maximal exercise.
MedLine Citation:
PMID:  8125877     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To determine the effect of maximal exercise on alveolocapillary membrane diffusing capacity (Dm), 12 professional handball players aged 23.4 +/- 3.3 (SD) yr were studied before and during early recovery from a progressive maximal exercise [immediately (t0), 15 min, and 30 min (t30) after exercise]. Lung capillary blood volume and Dm were determined in a one-step maneuver by simultaneous measurement of CO and NO lung transfer (DLCO and DLNO, respectively) with use of the single-breath breath-hold method. At t0, DLCO was elevated (13.1 +/- 12.0%; P < 0.01) but both DLNO and Dm for CO remained unchanged. Between t0 and t30, both DLCO and DLNO decreased significantly. At t30, DLCO was not different from the control resting value. DLNO (and consequently Dm for CO) was significantly lower than the control value at t30 (-8.9 +/- 8.1%; P < 0.01). Lung capillary blood volume was elevated at t0 (18.0 +/- 19.0%; P < 0.01) but progressively decreased to near control resting values at t30. Differences in the postexercise kinetics of both DLCO and DLNO point to a role of the transient increase in pulmonary vascular recruitment during the recovery period. We concluded that Dm was somewhat decreased in the 30 min after maximal exercise of short duration, but the exact pulmonary mechanisms involved remain to be elucidated.
Authors:
G Manier; J Moinard; H Stoïcheff
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of applied physiology (Bethesda, Md. : 1985)     Volume:  75     ISSN:  8750-7587     ISO Abbreviation:  J. Appl. Physiol.     Publication Date:  1993 Dec 
Date Detail:
Created Date:  1994-04-11     Completed Date:  1994-04-11     Revised Date:  2013-09-26    
Medline Journal Info:
Nlm Unique ID:  8502536     Medline TA:  J Appl Physiol (1985)     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  2580-5     Citation Subset:  IM    
Affiliation:
Laboratoire de Physiologie, Faculté de Médecine Victor Pachon, Université de Bordeaux II, France.
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MeSH Terms
Descriptor/Qualifier:
Adult
Blood Gas Analysis
Blood Volume / physiology
Carbon Monoxide / pharmacokinetics
Exercise / physiology*
Exercise Test
Heart Rate / physiology
Humans
Lung Volume Measurements
Male
Nitric Oxide / pharmacokinetics
Pulmonary Diffusing Capacity / physiology*
Chemical
Reg. No./Substance:
10102-43-9/Nitric Oxide; 630-08-0/Carbon Monoxide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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