Document Detail

Pulmonary damage associated with sodium aurothiomalate therapy.
MedLine Citation:
PMID:  411928     Owner:  NLM     Status:  MEDLINE    
Three patients with rheumatoid arthritis developed acute respiratory distress associated with pulmonary infiltration, during treatment with sodium aurothiomalate. This manifestation of gold toxicity has only recently been recognized. The temporal relationship to the introduction of gold therapy, an exacerbation following further gold injection in one patient, the resolution which followed gold withdrawal and the associated manifestation of gold toxicity in two patients favored a diagnosis of gold-induced pulmonary disease.
P W Gould; P L McCormack; D G Palmer
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of rheumatology     Volume:  4     ISSN:  0315-162X     ISO Abbreviation:  J. Rheumatol.     Publication Date:  1977  
Date Detail:
Created Date:  1978-01-27     Completed Date:  1978-01-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7501984     Medline TA:  J Rheumatol     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  252-60     Citation Subset:  IM    
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MeSH Terms
Arthritis, Rheumatoid / drug therapy
Gold Sodium Thiomalate / administration & dosage,  adverse effects*
Lung / drug effects*,  pathology,  radiography
Lung Diseases / chemically induced*
Middle Aged
Respiratory Function Tests
Time Factors
Reg. No./Substance:
12244-57-4/Gold Sodium Thiomalate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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