| Pulmonary complications of polymyositis and dermatomyositis. | |
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MedLine Citation:
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PMID: 17764062 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Polymyositis and dermatomyositis are systemic inflammatory diseases with unknown etiology and prognosis. Pulmonary involvement is increasingly recognized to be a major complication and a common cause of morbidity and mortality in these diseases. Thus a thorough pulmonary evaluation is necessary to permit appropriate management. There are three categories of pulmonary complications in myositis: aspiration pneumonia, hypoventilation, and interstitial lung disease (ILD). ILD is a frequent pulmonary complication in patients with myositis, and respiratory symptoms are not reliable signs for diagnosis. The strongest predictive factor for ILD in patients with myositis is the presence of antihistidyl transfer ribonucleic acid (tRNA) synthetase antibodies (anti-Jo-1), but ILD may also be present in patients without these autoantibodies. Therefore, all patients with polymyositis or dermatomyositis should be investigated with chest radiography, high-resolution computed tomography, and lung function tests. |
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Authors:
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Maryam Fathi; Ingrid E Lundberg; Göran Tornling |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Seminars in respiratory and critical care medicine Volume: 28 ISSN: 1069-3424 ISO Abbreviation: Semin Respir Crit Care Med Publication Date: 2007 Aug |
Date Detail:
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Created Date: 2007-09-03 Completed Date: 2007-11-08 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9431858 Medline TA: Semin Respir Crit Care Med Country: United States |
Other Details:
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Languages: eng Pagination: 451-8 Citation Subset: IM |
Affiliation:
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Department of Medicine, Division of Respiratory Medicine and Allergy, Karolinska University Hospital, Solna, Karolinska Institutet, Stockholm, Sweden. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Biological Markers Dermatomyositis / complications*, epidemiology, pathology Humans Hypoventilation / etiology Lung Diseases, Interstitial / diagnosis, etiology*, therapy Pneumonia, Aspiration / etiology Polymyositis / complications*, epidemiology, pathology Predictive Value of Tests Prognosis |
| Chemical | |
Reg. No./Substance:
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0/Biological Markers |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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