Document Detail


Pulmonary compliance changes after experimental head injury.
MedLine Citation:
PMID:  813014     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Reduced static compliance has been reported in the lungs of experimental animals removed immediately after head injury. To relate these findings to clinical human experience, pulmonary dynamic compliance measurements were continuously made by clinically applicable methods in 18 monkeys subjected to severe head trauma. After a 2-hr control period, the monkeys were given a standard blow on the head and followed for 2 more hours. Two monkeys died immediately after trauma and two during the succeeding two hours. Pulmonary compliance significantly decreased in these animals only at time of death. No change in compliance was noted in animals which did not die during the 2 hours of observation after trauma were killed by further trauma. These animals did not demonstrate decreased compliance. The findings suggest that the mechanical characteristics of the lungs following head trauma in experimental animals can be measured by methods used clincally and may remain unaltered until immediately before the time of death.
Authors:
M W Brueggemann; R G Loudon; R L McLaurin
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The Journal of trauma     Volume:  16     ISSN:  0022-5282     ISO Abbreviation:  J Trauma     Publication Date:  1976 Jan 
Date Detail:
Created Date:  1976-04-01     Completed Date:  1976-04-01     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0376373     Medline TA:  J Trauma     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  16-20     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Craniocerebral Trauma / complications,  physiopathology*
Disease Models, Animal
Haplorhini
Lung Compliance*
Macaca mulatta
Pulmonary Edema / etiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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