Document Detail


Pulmonary circulation demonstration using an isolated rat lung model.
MedLine Citation:
PMID:  16161230     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We have developed a pulmonary circulation laboratory exercise that effectively illustrates basic concepts typically taught in a graduate physiology curriculum. The demonstration uses an isolated, perfused rat lung model to delineate the mechanisms by which pulmonary vascular resistance can be altered either passively or in an active manner by contraction or relaxation of vascular smooth muscle. The exercise further offers an opportunity to closely observe an experimental preparation commonly used to study the pulmonary circulation and allows students the opportunity to interpret the resulting physiological data. Student evaluations indicate that the demonstration was received with enthusiasm and provides an effective teaching tool for reinforcing concepts in pulmonary vascular physiology.
Authors:
T C Resta; L M Eichinger; R D Russ; B R Walker
Publication Detail:
Type:  In Vitro; Journal Article; Review    
Journal Detail:
Title:  The American journal of physiology     Volume:  275     ISSN:  0002-9513     ISO Abbreviation:  Am. J. Physiol.     Publication Date:  1998 Dec 
Date Detail:
Created Date:  2005-09-14     Completed Date:  2005-10-04     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370511     Medline TA:  Am J Physiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  S85-95     Citation Subset:  IM    
Affiliation:
Departments of Cell Biology and Physiology, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131-5218, USA.
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MeSH Terms
Descriptor/Qualifier:
Animals
Education / methods*
Humans
Models, Animal*
Physiology / education*
Pulmonary Circulation*
Rats*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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