Document Detail

Pulmonary capillary leak associated with methylmethacrylate during general anesthesia. A case report.
MedLine Citation:
PMID:  7105557     Owner:  NLM     Status:  MEDLINE    
Noncardiogenic pulmonary edema (capillary leak syndrome) developed in a 61-year-old woman after methylmethacrylate was inserted for total hip replacement. The diagnosis was based on the low pulmonary artery and pulmonary artery wedge pressures, low systemic vascular resistance, relative hypovolemia, and clear pulmonary edema. The diagnosis of capillary leak syndrome can be confirmed by the finding of a protein composition of the pulmonary edema approximating that of plasma. The mechanism causing the capillary leak syndrome is unclear, but may be related to hypersensitivity, i.e., a previous hip arthroplasty, or to the release of vasoactive substances. Management consisted of fluid replacement to maintain cardiac output, and mechanical ventilation with positive end expiratory pressure to provide adequate oxygenation.
A M Safwat; A Dror
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Clinical orthopaedics and related research     Volume:  -     ISSN:  0009-921X     ISO Abbreviation:  Clin. Orthop. Relat. Res.     Publication Date:  1982 Aug 
Date Detail:
Created Date:  1982-10-12     Completed Date:  1982-10-12     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0075674     Medline TA:  Clin Orthop Relat Res     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  59-63     Citation Subset:  AIM; IM    
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MeSH Terms
Anesthesia, General
Hip Prosthesis*
Intraoperative Complications / chemically induced
Methylmethacrylates / adverse effects*
Middle Aged
Pulmonary Edema / chemically induced*,  physiopathology
Reg. No./Substance:

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