| Pulmonary blood volume and pulmonary extravascular water volume in men. | |
| | |
MedLine Citation:
|
PMID: 3894709 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
In order to estimate the pulmonary blood volume between the pulmonary artery trunk and the left atrium (PBV PAT-LA), simultaneously with the pulmonary extravascular water volume (PEWV) in the chronically stable cardiac patients, we employed the double indicator dilution method using heat as a diffusible indicator and indocyanine green as a non-diffusible indicator. The PEWV was obtained as the extravascular lung thermal volume estimated in the aortic root (LTVAo). In the group of hemodynamically normal patients, in spite of ischemic heart disease (G-N, n = 22), the mean pulmonary artery wedge (PAW) pressure was 9.3 +/- 3.9 mmHg (mean +/- SD), PBVPAT-LA was 8.95 +/- 1.71 ml/kg, LTVAo was 5.71 +/- 1.37 ml/kg and PBVPAT-LA/LTVAo ratio was 1.64 +/- 0.44. In the group of hemodynamically slightly compromised patients with mitral stenosis (G-MS, n = 13), the mean PAW pressure was 14.2 +/- 2.6 mmHg, PBVPAT-LA was 11.12 +/- 2.86 ml/kg, LTVAo was 5.68 +/- 1.41 ml/kg and PBVPAT-LA/LTVAo ratio was 2.02 +/- 0.58. Between the two groups, LTVAo was not statistically significant, whereas the mean PAW pressure, PBVPAT-LA and PBVPAT-LA/LTVAo ratio were all significantly increased in G-MS (p less than 0.05). Neither PBVPAT-LA nor LTVAo correlated with the mean PAW pressure in both groups. From PBVPAT-LA/LTVAo ratio, fluid volume in the intravascular space was greater than that in the extravascular space in both groups. From LTVAo, PEWV in G-MS was identical with that in G-N, in spite of the elevated mean PAW pressure. Therefore, even in the patients with mitral stenosis, the interstitium in the lung is kept "dry" under conditions of the mean PAW pressure below 20 mmHg. The safety factors that prevent pulmonary edema, as evidenced in animal studies, seem to operate effectively in man. |
| | |
Authors:
|
M Arakawa; Y Yasuda; K Kambara; J Iinuma; H Miyazaki; M Yamaguchi; T Takaya; T Nagano; M Goto; T Suzuki |
Related Documents
:
|
14518669 - Primary pulmonary hypertension treated with short-term epoprostenol infusion. 6600739 - Pulmonary blood flow distribution measured by radionuclide-computed tomography. 9762799 - Pulmonary haemodynamics in obstructive sleep apnoea: time course and associated factors. 19178599 - Pulmonary hypertension in chronic heart failure. 8004529 - Percutaneous balloon valvuloplasty for congenital critical pulmonary stenosis in neonates. 8239149 - Endothelin-1 in adult respiratory distress syndrome. 751439 - Measurement of endocardial viability ratio (e.v.r.) during anesthesia for cardiac surgery. 8458799 - Ventilatory response to moderate hypoxia in awake chemodenervated cats. 21597349 - Category i pressure ulcers how reliable is clinical assessment? |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Japanese circulation journal Volume: 49 ISSN: 0047-1828 ISO Abbreviation: Jpn. Circ. J. Publication Date: 1985 May |
Date Detail:
|
Created Date: 1985-09-16 Completed Date: 1985-09-16 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 7806868 Medline TA: Jpn Circ J Country: JAPAN |
Other Details:
|
Languages: eng Pagination: 475-86 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Blood Volume* Body Fluids / physiology* Cardiac Output Cardiac Volume* Coronary Disease / physiopathology* Dye Dilution Technique Heart Catheterization Humans Indicator Dilution Techniques Indocyanine Green / diagnostic use Lung / metabolism* Pulmonary Artery / physiopathology* Pulmonary Circulation Pulmonary Wedge Pressure Thermodilution |
| Chemical | |
Reg. No./Substance:
|
3599-32-4/Indocyanine Green |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Comparison of single-dose vs one-week course of metronidazole for symptomatic bacterial vaginosis.
Next Document: Current diagnosis of infective endocarditis.