Document Detail


Pulmonary artery sarcoma: an insidious tumor still diagnosed too late. Analysis of the literature and report of a case.
MedLine Citation:
PMID:  17550145     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Pulmonary artery sarcoma is an exceptionally rare tumor which must be considered in the differential diagnosis of pulmonary thromboembolism. We report the case of a 36-year-old woman and review 100 cases published in the literature between 1988 and 2005. The patient presented with a history of dyspnea, fatigue, fever, night sweats and anemia that did not respond to antibiotic therapy. She also had hemoptysis. Transvenous catheter biopsy was indicative of sarcoma. A left pneumonectomy was performed, followed by five cycles of chemotherapy. Histological and immunohistochemical studies documented an intimal sarcoma with myofibroblastic differentiation. The patient is alive and well 20 months after surgery. The clinico-pathological features of pulmonary artery sarcoma are described.
Authors:
A Coli; P Parente; G Bigotti
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Journal of experimental & clinical cancer research : CR     Volume:  26     ISSN:  0392-9078     ISO Abbreviation:  J. Exp. Clin. Cancer Res.     Publication Date:  2007 Mar 
Date Detail:
Created Date:  2007-06-06     Completed Date:  2007-06-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8308647     Medline TA:  J Exp Clin Cancer Res     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  151-6     Citation Subset:  IM    
Affiliation:
Department of Pathology, Catholic University Sacro Cuore, Rome, Italy. antonella.coli@rm.unicatt.it
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MeSH Terms
Descriptor/Qualifier:
Adult
Anemia / etiology
Antineoplastic Agents / therapeutic use
Diagnosis, Differential
Dyspnea / etiology
Fatigue / etiology
Female
Fever / etiology
Hemoptysis / etiology
Humans
Pneumonectomy
Pulmonary Artery / pathology*
Pulmonary Embolism / diagnosis*
Sarcoma / complications,  diagnosis*,  drug therapy,  pathology,  surgery
Treatment Outcome
Vascular Neoplasms / complications,  diagnosis*,  drug therapy,  pathology,  surgery
Chemical
Reg. No./Substance:
0/Antineoplastic Agents

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