Document Detail

Pulmonary artery pressure and lung water during extracorporeal circulation in experimental pulmonary insufficiency.
MedLine Citation:
PMID:  1099997     Owner:  NLM     Status:  MEDLINE    
Use of the membrane oxggenator has been advocated in the management of severe respiratory insufficiency. We have compared this method to conventional therapy in an experimental model in which 23 dogs were subjected to aspiration with 0.1 N HC1 and 18 were supported with a volume respirator and positive end-expiratory pressure or placed on partial bypass using a membrane oxygenator for 12 to 24 hours. Adequate oxygenation (POX greater than 100 mm Hg) was achieved with the membrane oxygenator. The increase in lung weight during conventional therapy was significantly greater than during membrane oxygenator support. Extracorporeal support during recovery from severe pulmonary injury allows pulmonary artery pressure to be controlled and reduces the expected increase in lung water.
B Brandt; B Doyle; H Weintraub; H Harrison
Related Documents :
3185307 - Contribution of capillary recruitment to regulation of tissue oxygenation in rat cremas...
6986237 - Changes in intrapulmonary shunting with administration of 100 percent oxygen.
12559587 - Scientific and technological aspects of oxygen-sensitive electrodes for measurements of...
11837787 - Induced hypothermia after high-energy soft-tissue injury and subsequent hemorrhagic shock.
7094597 - Failure of one method of simultaneous chest compression, ventilation, and abdominal bin...
6465427 - Is femoral pulse palpation accurate in assessing the hemodynamic significance of aortoi...
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  20     ISSN:  0003-4975     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  1975 Sep 
Date Detail:
Created Date:  1975-11-22     Completed Date:  1975-11-22     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  308-15     Citation Subset:  AIM; IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Blood Pressure*
Disease Models, Animal
Extracorporeal Circulation*
Lung / metabolism*
Lung Compliance
Organ Size
Oxygen / blood
Oxygenators, Membrane
Pneumonia, Aspiration / metabolism,  mortality,  physiopathology
Positive-Pressure Respiration
Pulmonary Artery / physiology*
Respiration, Artificial
Respiratory Insufficiency / metabolism,  mortality,  physiopathology*
Water / metabolism*
Water-Electrolyte Balance
Reg. No./Substance:
7732-18-5/Water; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Correction of the transposition of the great arteries.
Next Document:  Cardiovascular effects of central microinjections of apomorphin in cats.