Document Detail


Pulmonary artery pressure and lung water during extracorporeal circulation in experimental pulmonary insufficiency.
MedLine Citation:
PMID:  1099997     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Use of the membrane oxggenator has been advocated in the management of severe respiratory insufficiency. We have compared this method to conventional therapy in an experimental model in which 23 dogs were subjected to aspiration with 0.1 N HC1 and 18 were supported with a volume respirator and positive end-expiratory pressure or placed on partial bypass using a membrane oxygenator for 12 to 24 hours. Adequate oxygenation (POX greater than 100 mm Hg) was achieved with the membrane oxygenator. The increase in lung weight during conventional therapy was significantly greater than during membrane oxygenator support. Extracorporeal support during recovery from severe pulmonary injury allows pulmonary artery pressure to be controlled and reduces the expected increase in lung water.
Authors:
B Brandt; B Doyle; H Weintraub; H Harrison
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  20     ISSN:  0003-4975     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  1975 Sep 
Date Detail:
Created Date:  1975-11-22     Completed Date:  1975-11-22     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  308-15     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Blood Pressure*
Disease Models, Animal
Dogs
Extracorporeal Circulation*
Lung / metabolism*
Lung Compliance
Organ Size
Oxygen / blood
Oxygenators, Membrane
Perfusion
Pneumonia, Aspiration / metabolism,  mortality,  physiopathology
Positive-Pressure Respiration
Pulmonary Artery / physiology*
Respiration, Artificial
Respiratory Insufficiency / metabolism,  mortality,  physiopathology*
Water / metabolism*
Water-Electrolyte Balance
Chemical
Reg. No./Substance:
7732-18-5/Water; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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