Document Detail


Pulmonary artery involvement in Takayasu's arteritis with lung infarction and pulmonary aspergillosis.
MedLine Citation:
PMID:  17041382     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
We describe a patient with a chronic case of pulmonary involvement of Takayasu's arteritis in the resected lung. A 49-year-old woman was first diagnosed with Takayasu's arteritis at age 30 years. On her first admission, she presented with Takayasu's arteritis and pneumonia with cavitation in the left lung. After recovering from pneumonia, she was treated initially with prednisolone, 30 mg/day, and remained well until she developed hemoptysis at age 34 years. Findings suggesting aspergilloma were found in the same lobe on chest x-ray film when she was 46 years of age. By age 49 years, the hemoptysis became massive, and she was admitted for surgery. Left upper lobectomy and partial resection of S6 and S8 pulmonary segments were performed. Histologic analysis of the resected lung revealed typical pathologic findings of pulmonary artery involvement in Takayasu's arteritis, such as stenosis recanalization and a vessel-in-vessel feature, but not active vasculitis. Infection probably occurred in the cavity of the infarcted tissue. Pulmonary artery involvement is common in Takayasu's arteritis, but the aspergilloma in this corticosteroid-treated patient is an uncommon complication.
Authors:
Jun-Ichi Narita; Satoshi Ito; Masaki Terada; Yasuharu Saitoh; Ken-Ichi Igarashi; Masaaki Nakano; Eiichi Suzuki; Masaaki Arakawa; Fumitake Gejyo
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases     Volume:  8     ISSN:  1076-1608     ISO Abbreviation:  J Clin Rheumatol     Publication Date:  2002 Oct 
Date Detail:
Created Date:  2006-10-16     Completed Date:  2007-07-10     Revised Date:  2008-04-10    
Medline Journal Info:
Nlm Unique ID:  9518034     Medline TA:  J Clin Rheumatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  260-4     Citation Subset:  -    
Affiliation:
Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata City, Japan.
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