| Pulmonary arteritis with pulmonary arterial thrombosis and recurrent endopulmonary embolization. | |
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MedLine Citation:
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PMID: 8374250 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A 41-year-old woman underwent medical examination for superficial thrombophlebitis of both lower legs. Incidentally a chronic myelogenous leukemia was diagnosed and chemotherapeutically treated. Three weeks after the first attendance the patient again suffered superficial thrombophlebitides of all extremities. Clinically she exhibited symptoms of recurrent mild pulmonary embolization. Contrast venography revealed no signs of deep venous thrombosis of legs, pelvis, or cava inferior. Despite continuous full-dose intravenous heparin administration the patient died, with signs of fulminant pulmonary embolization. Surprisingly, necropsy revealed a complete thrombotic occlusion of the pulmonary arterial system caused by pulmonary arteritis with signs of recurrent pulmonary embolization from a parietal truncus pulmonalis thrombosis. In addition, an appositional growth of parietal thrombi central from peripheral arterial ramifications had occurred. Simultaneously, superficial thrombophlebitis of all extremities was observed without any additional signs of general vasculitis. There was no strong evidence for a causal relationship between the chronic myelogenous leukemia and pulmonary arteritis nor for any other underlying systemic disorder. Therefore we consider the pulmonary arteritis a possibly primary one. This very rare disease is discussed with respect to the literature. |
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Authors:
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U Wagner; A Bittinger; P von Wichert; P J Barth |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: The Clinical investigator Volume: 71 ISSN: 0941-0198 ISO Abbreviation: Clin Investig Publication Date: 1993 Jul |
Date Detail:
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Created Date: 1993-10-19 Completed Date: 1993-10-19 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9207154 Medline TA: Clin Investig Country: GERMANY |
Other Details:
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Languages: eng Pagination: 559-63 Citation Subset: IM |
Affiliation:
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Zentrum für Innere Medizin, Medizinische Poliklinik, Philipps-Universität Marburg. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Arteritis / complications*, pathology Autopsy Female Humans Leukemia, Myelogenous, Chronic, BCR-ABL Positive / complications Lung / blood supply*, pathology Pulmonary Artery / pathology Pulmonary Circulation Pulmonary Embolism / complications* Recurrence Thrombophlebitis / complications, pathology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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