Document Detail


Pulmonary arteriovenous malformations related to Rendu-Osler-Weber syndrome.
MedLine Citation:
PMID:  6496570     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Interest in Rendu-Osler-Weber (ROW) syndrome has been renewed because of new treatment for the pulmonary artery fistulae that occur in approximately one-half of the patients. Pulmonary arteriovenous malformations (AVM) can be occluded safely by the transvenous placement of a silicone balloon thus avoiding the many potential complications of thoracotomy. Thirty-three members of four generations of a family with ROW illustrate the varied manifestations of the syndrome and provide a basis for review of clinical findings and therapeutic approaches to the management of pulmonary AVMs during the last 25 years. Special attention is given to early detection and prevention of major complications. Since ROW syndrome is an inherited trait, informed genetic counseling is an important component of the overall management of families with this disorder.
Authors:
C M McCue; M Hartenberg; W E Nance
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  American journal of medical genetics     Volume:  19     ISSN:  0148-7299     ISO Abbreviation:  Am. J. Med. Genet.     Publication Date:  1984 Sep 
Date Detail:
Created Date:  1984-12-12     Completed Date:  1984-12-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7708900     Medline TA:  Am J Med Genet     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  19-27     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Arteriovenous Malformations / complications,  diagnosis*,  surgery
Female
Humans
Male
Pedigree
Pulmonary Artery / abnormalities*,  surgery
Pulmonary Veins / abnormalities*,  surgery
Syndrome
Telangiectasia, Hereditary Hemorrhagic / complications,  genetics*

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