| Pulmonary arterial thrombosis in secundum atrial septal defect. | |
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MedLine Citation:
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PMID: 3687745 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Nineteen adolescent or adult patients with secundum atrial septal defect (ASD) underwent pulmonary arteriography to evaluate the presence of proximal pulmonary arterial (PA) thrombosis. This procedure demonstrated proximal PA thrombosis in 8 patients (group 2). These patients had a distinctive hemodynamic profile, consisting primarily of significant PA hypertension. None of the 11 patients with normal angiograms (group 1) had severe PA hypertension (p less than 0.0001). Proximal PA thrombosis appears to be the major factor in the development and progression of PA hypertension in adult patients with ostium secundum ASD. Pulmonary angiography should be undertaken in all adult patients with ostium secundum ASD who have at least moderate PA hypertension. Long-term anticoagulation is advocated for patients with PA thrombosis irrespective of a decision for surgical intervention. |
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Authors:
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C L Schamroth; P Sareli; W A Pocock; R Davidoff; J King; G S Reinach; J B Barlow |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The American journal of cardiology Volume: 60 ISSN: 0002-9149 ISO Abbreviation: Am. J. Cardiol. Publication Date: 1987 Nov |
Date Detail:
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Created Date: 1987-12-23 Completed Date: 1987-12-23 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0207277 Medline TA: Am J Cardiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1152-6 Citation Subset: AIM; IM |
Affiliation:
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University of the Witwatersrand, South Africa. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Blood Pressure Female Heart Septal Defects, Atrial / complications* Humans Hypertension, Pulmonary / etiology, physiopathology, radiography Male Middle Aged Pulmonary Artery* / radiography Thrombosis / complications*, radiography Vascular Resistance |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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