Document Detail


Pulmonary arterial pressure in children with allergic rhinitis.
MedLine Citation:
PMID:  15490569     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Chronic upper airway obstruction may lead to increased pulmonary arterial pressure in childhood. Allergic rhinitis is one of the frequent causes of upper airway obstruction by nasal blockage. The aims of the study were to evaluate the pulmonary arterial pressures in children with allergic rhinitis and the effect of topical corticosteroid therapy. METHODS: Forty-nine children composed of 27 subjects with seasonal and 22 subjects with perennial allergic rhinitis were enrolled in this study. The pulmonary arterial pressures were measured by using Doppler echocardiography. RESULTS: The pretreatment pulmonary arterial systolic, mean, and diastolic pressures of study group were significantly higher than in healthy controls (p < 0.05). The pulmonary arterial systolic and mean pressures of the patient group significantly decreased at the end of study (p < 0.05), whereas the decrease of the diastolic pressure was not statistically significant (p > 0.05) after the treatment of a topical corticosteroid, mometasone furoate (100 microg per day), for 8 weeks. CONCLUSION: Our results showed that children with allergic rhinitis have higher pulmonary arterial pressure levels compared with healthy controls and that increased pulmonary arterial pressure levels due to allergic rhinitis are reversible by using nasal topical corticosteroids. Further studies are needed to determine the clinical aspect of increased pulmonary arterial pressure.
Authors:
Ismail Reisli; Bulent Oran; Osman Baspinar; Tamer Baysal; Sevim Karaaslan
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of rhinology     Volume:  18     ISSN:  1050-6586     ISO Abbreviation:  Am J Rhinol     Publication Date:    2004 Jul-Aug
Date Detail:
Created Date:  2004-10-19     Completed Date:  2004-12-16     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  8807268     Medline TA:  Am J Rhinol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  227-32     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Meram Medical Faculty, University of Selcuk, Konya, Turkey.
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MeSH Terms
Descriptor/Qualifier:
Anti-Allergic Agents / therapeutic use
Blood Pressure*
Child
Echocardiography, Doppler
Female
Humans
Male
Nasal Obstruction / etiology,  physiopathology
Pregnadienediols / therapeutic use
Pulmonary Artery*
Rhinitis, Allergic, Perennial / drug therapy,  physiopathology*
Rhinitis, Allergic, Seasonal / drug therapy,  physiopathology*
Chemical
Reg. No./Substance:
0/Anti-Allergic Agents; 0/Pregnadienediols; 83919-23-7/mometasone furoate

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