Document Detail


Pulmonary arterial hypertension.
MedLine Citation:
PMID:  22035608     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Pulmonary hypertension is a complex and multidisciplinary disorder. The classification of pulmonary hypertension includes 5 groups. Pulmonary arterial hypertension is a rare disorder that can be idiopathic or heritable in nature, or associated with other conditions, such as scleroderma or congenital heart disease. The recent decades have realized advances in the treatment of this once devastating disease. More commonly, pulmonary hypertension is associated with other disorders, such as those that elevate left heart filling pressures and hypoxemic lung disease. Chronic thromboembolic disease can result in pulmonary hypertension. To determine the etiology, a thorough and methodical evaluation must be completed. Often, an echocardiogram is the first test to suggest the diagnosis of pulmonary hypertension. Studies to identify potential associated causes are important. The diagnostic evaluation culminates in right heart catheterization. Over recent years, advances in therapies, including the prostacyclins, the endothelin receptor antagonists, and the phosphodiesterase type 5 inhibitors, have resulted in an improved quality of life and outlook for patients with what is often a progressive disease.
Authors:
Vallerie V McLaughlin; Melinda Davis; William Cornwell
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Current problems in cardiology     Volume:  36     ISSN:  1535-6280     ISO Abbreviation:  Curr Probl Cardiol     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-10-31     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7701802     Medline TA:  Curr Probl Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  461-517     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Mosby, Inc. All rights reserved.
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