Document Detail

Pulmonary arterial hypertension in congenital heart disease.
MedLine Citation:
PMID:  12371012     Owner:  NLM     Status:  MEDLINE    
Pulmonary arterial hypertension (PAH) is a recognized complication of congenital systemic to pulmonary arterial cardiac shunts. The prognosis of PAH in this situation is better than primary or other secondary forms of PAH. Our knowledge of the pathophysiology of PAH complicating congenital heart disease has evolved over the past decade. Despite differences in etiology and pathobiology, therapies that have proven successful for primary PAH may benefit this group of patients.
John T Granton; Marlene Rabinovitch
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Cardiology clinics     Volume:  20     ISSN:  0733-8651     ISO Abbreviation:  Cardiol Clin     Publication Date:  2002 Aug 
Date Detail:
Created Date:  2002-10-09     Completed Date:  2003-02-04     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8300331     Medline TA:  Cardiol Clin     Country:  United States    
Other Details:
Languages:  eng     Pagination:  441-57, vii     Citation Subset:  IM    
Department of Medicine, University of Toronto, Division of Respirology and Critical Care Medicine Programme, University Health Network, 10 EN-220, 200 Elizabeth Street, Toronto, Ontario, Canada M5G 2C4.
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MeSH Terms
Eisenmenger Complex / complications*,  therapy
Endothelins / antagonists & inhibitors*
Endothelium, Vascular / physiopathology*
Hypertension, Pulmonary / complications*,  diagnosis,  genetics,  therapy*
Pulmonary Artery
Risk Factors
Vasoconstriction / physiology*
Vasodilator Agents / therapeutic use*
Reg. No./Substance:
0/Endothelins; 0/Vasodilator Agents

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