Document Detail


Pulmonary arterial hypertension--contemporary management strategy.
MedLine Citation:
PMID:  20017449     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Pulmonary arterial hypertension (PAH) is a severe chronic disorder of pulmonary arteries with progressive precapillary pulmonary hypertension, characterized by poor life quality and very poor prognosis. Unless treated, it causes death within 2-3 years from diagnosis. PAH affects mainly younger women. The treatment of PAH should not only be symptomatic, but also directed towards the improvement in patient's survival and quality of life. Many novel drugs putting together so called specific PAH therapy (endothelin receptor antagonists, prostanoids, phosphodiesterase--5 inhibitors) were tested in randomized trials. PAH management requires a highly individualized approach, state of the art knowledge and adequate experience. Patients therefore should be referred to specialized PAH centers providing both complete diagnosis and therapy. In our region a close co-operation between Czech and Slovak PAH centers has also proved to be profitable. Data sources. Literature retrieval was accessed through MEDLINE using the terms pulmonary hypertension, PAH, diagnosis, treatment. Reference citations from publications identified were reviewed (Ref. 47). Full Text (Free, PDF) www.bmj.sk.
Authors:
P Jansa; D Ambroz; J Maresova; P Polacek; M Aschermann; A Linhart
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Bratislavské lekárske listy     Volume:  110     ISSN:  0006-9248     ISO Abbreviation:  Bratisl Lek Listy     Publication Date:  2009  
Date Detail:
Created Date:  2009-12-18     Completed Date:  2010-01-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0065324     Medline TA:  Bratisl Lek Listy     Country:  Slovakia    
Other Details:
Languages:  eng     Pagination:  603-8     Citation Subset:  IM    
Affiliation:
Charles University, 1st Faculty of Medicine, 2nd Medical Department, Clinical Department of Cardiology and Angiology, Prague, Czech Republic. jansapavel@yahoo.com
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MeSH Terms
Descriptor/Qualifier:
Humans
Hypertension, Pulmonary / diagnosis,  therapy*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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