Document Detail

Pulmonary alveolar proteinosis: step-by-step perioperative care of whole lung lavage procedure.
MedLine Citation:
PMID:  11805749     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Pulmonary alveolar proteinosis is a rare disease characterized by the accumulation of surfactant-like material within the alveolar spaces that causes progressive respiratory failure. Improvement can be achieved with whole lung lavage. OBJECTIVE: Our objective was to conduct a study of the feasibility of treating pulmonary alveolar proteinosis in a community hospital. METHODS: Five patients were treated. We assessed procedure pulmonary functions. RESULTS: No major sequelae occurred. Each lung was lavaged with 12 to 20 L of normal saline in cycles of 970 +/- 150 mL each (mean +/- standard deviation), over 106 +/- 49 minutes. Extubation was performed when compliance of the lavaged lung was restored. All patients showed subjective improvement. Resting and exercise oxygen saturation improved within 1 week after the lavage. A significant improvement was also noted in forced expiratory volume in 1 second, forced vital capacity, and maximal oxygen uptake, whereas total lung capacity and carbon monoxide single-breath diffusion capacity remained unchanged. CONCLUSION: Although retrospective and based on a small sample size, our results suggest that whole lung lavage may be performed safely even in medical centers that have limited experience, if strict adherence to a protocol is maintained.
Ron Ben-Abraham; Adrian Greenfeld; Judith Rozenman; Issahar Ben-Dov
Related Documents :
21154789 - Limitation of physical performance in a muscle fatiguing handgrip exercise is mediated ...
1990939 - Increased levels of oxidized methionine residues in bronchoalveolar lavage fluid protei...
9354509 - Cardiopulmonary function at rest and during exercise after resection for bronchial carc...
3512509 - Estimation of volume of epithelial lining fluid recovered by lavage using urea as marke...
7820979 - Biphasic pulmonary clearance of 99mtc-dtpa in smokers.
3975499 - Lung volume changes during respiration in ducks.
25217819 - Development of a risk-screening tool for cancer survivors to participate in unsupervise...
16547999 - Enhanced lycopene production in escherichia coli engineered to synthesize isopentenyl d...
19374309 - Effect of lower extremity exercise on muscle strength and physical capacity in copd pat...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Heart & lung : the journal of critical care     Volume:  31     ISSN:  0147-9563     ISO Abbreviation:  Heart Lung     Publication Date:    2002 Jan-Feb
Date Detail:
Created Date:  2002-01-23     Completed Date:  2002-03-13     Revised Date:  2006-08-28    
Medline Journal Info:
Nlm Unique ID:  0330057     Medline TA:  Heart Lung     Country:  United States    
Other Details:
Languages:  eng     Pagination:  43-9     Citation Subset:  AIM; IM    
Department of Anesthesiology and Critical Care, Faculty of Medicine, Tel Aviv University, Israel.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Bronchoalveolar Lavage / methods*
Feasibility Studies
Hospitals, Community
Middle Aged
Perioperative Care / methods*
Pulmonary Alveolar Proteinosis / therapy*
Quality of Health Care
Retrospective Studies
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Decreased activity and oxygen desaturation in prone ventilated preterm infants during the first post...
Next Document:  Pneumocystis carinii pneumonia presenting as a fever of unknown origin in a patient without AIDS.