| Pulmonary alveolar proteinosis: step-by-step perioperative care of whole lung lavage procedure. | |
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MedLine Citation:
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PMID: 11805749 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Pulmonary alveolar proteinosis is a rare disease characterized by the accumulation of surfactant-like material within the alveolar spaces that causes progressive respiratory failure. Improvement can be achieved with whole lung lavage. OBJECTIVE: Our objective was to conduct a study of the feasibility of treating pulmonary alveolar proteinosis in a community hospital. METHODS: Five patients were treated. We assessed procedure pulmonary functions. RESULTS: No major sequelae occurred. Each lung was lavaged with 12 to 20 L of normal saline in cycles of 970 +/- 150 mL each (mean +/- standard deviation), over 106 +/- 49 minutes. Extubation was performed when compliance of the lavaged lung was restored. All patients showed subjective improvement. Resting and exercise oxygen saturation improved within 1 week after the lavage. A significant improvement was also noted in forced expiratory volume in 1 second, forced vital capacity, and maximal oxygen uptake, whereas total lung capacity and carbon monoxide single-breath diffusion capacity remained unchanged. CONCLUSION: Although retrospective and based on a small sample size, our results suggest that whole lung lavage may be performed safely even in medical centers that have limited experience, if strict adherence to a protocol is maintained. |
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Authors:
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Ron Ben-Abraham; Adrian Greenfeld; Judith Rozenman; Issahar Ben-Dov |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Heart & lung : the journal of critical care Volume: 31 ISSN: 0147-9563 ISO Abbreviation: Heart Lung Publication Date: 2002 Jan-Feb |
Date Detail:
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Created Date: 2002-01-23 Completed Date: 2002-03-13 Revised Date: 2006-08-28 |
Medline Journal Info:
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Nlm Unique ID: 0330057 Medline TA: Heart Lung Country: United States |
Other Details:
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Languages: eng Pagination: 43-9 Citation Subset: AIM; IM |
Affiliation:
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Department of Anesthesiology and Critical Care, Faculty of Medicine, Tel Aviv University, Israel. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Bronchoalveolar Lavage / methods* Feasibility Studies Female Hospitals, Community Humans Israel Male Middle Aged Perioperative Care / methods* Pulmonary Alveolar Proteinosis / therapy* Quality of Health Care Retrospective Studies Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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