Document Detail


Pulmonary alveolar proteinosis: a report of seven patients from King Chulalongkorn Memorial Hospital.
MedLine Citation:
PMID:  16623047     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
From 1983 to 2001, 7 patients with pulmonary alveolar proteinosis were admitted to the King Chulalongkorn Memorial Hospital. Presenting symptoms varied from asymptomatic (1 patient), progressive dyspnea on exertion (4 patients) to respiratory failure (2 patients). Other symptoms included dry cough and weight loss. Gradual onset of dyspnea could be observed by average time to hospital (7 months). Early worsening of dyspnea and high-grade fever suggested a possibility of superimposed infection. Chest radiographs revealed symmetrical infiltration without lobar predominance. 4 of 7 patients were misdiagnosed as pulmonary tuberculosis before diagnosis of PAP was made. Diagnosis was made by bronchoscopic examination with typical lavage fluid or pathological results; only one case need open lung biopsy. 6 of 7 patients required lung lavage to relieve dyspneic symptoms. Coinfection with Nocardia and Mycobacterium tuberculosis was found in one patient. Prognosis was good but recurrence was common.
Authors:
Kamon Kawkitinarong; Chanchai Sittipunt; Somkiat Wongtim; Visit Udompanich
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the Medical Association of Thailand = Chotmaihet thangphaet     Volume:  88 Suppl 4     ISSN:  0125-2208     ISO Abbreviation:  J Med Assoc Thai     Publication Date:  2005 Sep 
Date Detail:
Created Date:  2006-04-20     Completed Date:  2006-05-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7507216     Medline TA:  J Med Assoc Thai     Country:  Thailand    
Other Details:
Languages:  eng     Pagination:  S312-6     Citation Subset:  IM    
Affiliation:
Division of Pulmonary and Critical Care Medicine, Department of Medicine, Chulalongkorn University, Bangkok, Thailand. fmedkkk@md.chula.ac.th
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Bronchoalveolar Lavage
Bronchoscopy
Disease Progression
Female
Humans
Male
Middle Aged
Pulmonary Alveolar Proteinosis / diagnosis*
Pulmonary Alveoli / physiopathology*
Retrospective Studies
Thailand

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