| Pulmonary alveolar proteinosis in extremis: the case for aggressive whole lung lavage with extracorporeal membrane oxygenation support. | |
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MedLine Citation:
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PMID: 17337244 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Pulmonary alveolar proteinosis (PAP) is a rare disorder in which lipoproteinaceous material is deposited in the alveoli, compromising gaseous exchange. We report the case of a 29-year-old female patient presenting with the most extreme case of PAP yet reported. She successfully managed by aggressive bilateral whole lung lavage (WLL) in a single sitting using extracorporeal membrane oxygenation (ECMO) support. Despite critical hypercarbia and ventilator-dependence for 12 days before lavage, the patient experienced rapid recovery of pulmonary function after WLL and ECMO could be discontinued on-table. Aggressive WLL with ECMO support can be safe and effective even in the most severe cases of PAP. |
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Authors:
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Alan D L Sihoe; Vivian M W Ng; Raymond W T Liu; Lik-Cheung Cheng |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2007-03-06 |
Journal Detail:
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Title: Heart, lung & circulation Volume: 17 ISSN: 1444-2892 ISO Abbreviation: Heart Lung Circ Publication Date: 2008 Feb |
Date Detail:
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Created Date: 2007-12-18 Completed Date: 2008-03-26 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 100963739 Medline TA: Heart Lung Circ Country: Australia |
Other Details:
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Languages: eng Pagination: 69-72 Citation Subset: IM |
Affiliation:
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Division of Cardiothoracic Surgery, The University of Hong Kong, Grantham Hospital, Hong Kong SAR, China. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Bronchoalveolar Lavage / methods Bronchoscopy Disease Progression Extracorporeal Membrane Oxygenation / methods* Female Fiber Optic Technology Follow-Up Studies Humans Pulmonary Alveolar Proteinosis / diagnosis*, therapy* Pulmonary Gas Exchange Radiography, Thoracic Respiration, Artificial / methods Risk Assessment Severity of Illness Index Tomography, X-Ray Computed Treatment Outcome |
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