Document Detail

Pulmonary alveolar microlithiasis. A case report with a discussion of differential diagnosis.
MedLine Citation:
PMID:  500384     Owner:  NLM     Status:  MEDLINE    
The rare disease of pulmonary alveolar microlithiasis is characterized by innumerable microscopic stones, mainly of tribasic calcium phosphate, within the pulmonary alveoli. In a 13-year-old boy an earlier radiological examination showed diffuse lung opacity. The main differential diagnoses taken into consideration were sarcoidosis, idiopathic hemosiderosis, diffuse interstitial fibrosis and alveolar proteinosis. The correct diagnosis was made after a lung biopsy which showed intra-alveolar microliths. The radiological findings are in agreement with the reports in the literature. The specific X-ray features of pulmonary alveolar microlithiasis are calcified opacities, nodules, hilifugal trabeculations and pleural striae. These radiological signs are sufficiently diagnostic to restrict lung biopsy to particularly difficult cases. The disease is resistant to all therapeutic measures.
V Saputo; M Zocchi; M Mancosu; U Bonaldi; P Croce
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Helvetica paediatrica acta     Volume:  34     ISSN:  0018-022X     ISO Abbreviation:  Helv Paediatr Acta     Publication Date:  1979  
Date Detail:
Created Date:  1980-01-19     Completed Date:  1980-01-19     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0373005     Medline TA:  Helv Paediatr Acta     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  245-55     Citation Subset:  IM    
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MeSH Terms
Calculi / pathology,  radiography*,  surgery
Diagnosis, Differential
Hemosiderosis / radiography
Lung Diseases / pathology,  radiography*,  surgery
Pulmonary Alveolar Proteinosis / radiography
Pulmonary Alveoli / pathology,  radiography*,  surgery
Pulmonary Fibrosis / radiography
Respiratory Function Tests
Sarcoidosis / radiography

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