Document Detail

Pulmonary abscesses in congenital syphilis.
MedLine Citation:
PMID:  11900580     Owner:  NLM     Status:  MEDLINE    
Congenital syphilis remains a public health concern in the United States. Infants whose mothers are treated in the third trimester without adequate prenatal care have an increased risk of morbidity and mortality in the immediate perinatal period. The identification of Treponema pallidum in tissue is definitive confirmation of infection. We report the case of a 32-week gestational age infant born to a mother treated for syphilis 7 days prior to delivery. The infant died 12.5 hours after birth. At autopsy, there was extensive acute hyaline membrane disease. In addition, there were bilateral pulmonary abscesses with spirochetes. The onset of maternal disease was unknown, but was probably early in or prior to the pregnancy. This is an unusual case of pulmonary involvement in congenital syphilis.
Carrie Bell; Jerome Taxy
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Archives of pathology & laboratory medicine     Volume:  126     ISSN:  0003-9985     ISO Abbreviation:  Arch. Pathol. Lab. Med.     Publication Date:  2002 Apr 
Date Detail:
Created Date:  2002-03-19     Completed Date:  2002-05-10     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7607091     Medline TA:  Arch Pathol Lab Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  484-6     Citation Subset:  AIM; IM    
Wayne State University, School of Medicine, Detroit, MI, USA.
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MeSH Terms
Fatal Outcome
Gestational Age
Infant, Newborn
Infant, Premature*
Lung Abscess / etiology,  pathology*
Pregnancy Complications, Infectious*
Syphilis, Congenital / complications,  pathology*
Treponema pallidum / isolation & purification

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