Document Detail

Pulmonary Scopulariopsis in a chronic tobacco smoker.
MedLine Citation:
PMID:  20848053     Owner:  NLM     Status:  MEDLINE    
A 70-year-old male smoker, with a three-month status of post-balloon angioplasty for ischaemic heart disease, presented with a one-week history of fever, haemoptysis and chest discomfort on coughing. The patient did not report any loss of weight or appetite. On examination, he was febrile. Pulmonary function tests revealed obstructive airway disease. High resolution computed tomography of the lungs revealed fibrosis with bronchiectasis in both the upper lobes, and a spiculating subpleural mass in the posterior aspect of the right lung apex. Subsequent bronchoalveolar lavage (BAL) culture yielded the Scopulariopsis species. Our patient was treated with a four-week course of amphotericin B, followed by itraconazole. At the 24-month follow-up, the patient was asymptomatic. Subsequent BAL cultures revealed no fungal growths, and radiological studies showed a regression in the lesion.
M Satyavani; R Viswanathan; N S Harun; L Mathew
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Singapore medical journal     Volume:  51     ISSN:  0037-5675     ISO Abbreviation:  Singapore Med J     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-09-17     Completed Date:  2011-01-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0404516     Medline TA:  Singapore Med J     Country:  Singapore    
Other Details:
Languages:  eng     Pagination:  e137-9     Citation Subset:  IM    
Department of Laboratory Services, Raja Isteri Pengiran Anak Saleha Hospital, Ministry of Health, Bandar Seri Begawan, BA 1710 Brunei Darussalam.
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MeSH Terms
Antifungal Agents / therapeutic use
Biopsy, Fine-Needle
Bronchoalveolar Lavage Fluid / microbiology*
Lung Diseases, Fungal / complications,  drug therapy,  radiography*
Saccharomycetales / isolation & purification*
Tomography, X-Ray Computed
Reg. No./Substance:
0/Antifungal Agents

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