Document Detail


Pulmonary Histoplasmosis.
MedLine Citation:
PMID:  11384559     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Most patients with pulmonary histoplasmosis experience a self-limited illness that rarely requires treatment. However, patients who inhale a large burden of organisms from the environment and those who are immunosuppressed may develop severe, life-threatening pneumonia. Chronic histoplasmosis occurs almost exclusively in patients with severe chronic obstructive pulmonary disease. Complications of pulmonary histoplasmosis are mostly related to persistent mediastinal lymphadenopathy. Mild to moderate forms of pulmonary histoplasmosis should be treated with itraconazole. Patients with severe pulmonary involvement should initially receive amphotericin B; after the patient's condition has improved, therapy can be changed to itraconazole. Preventive measures should be used to protect workers from exposure to large numbers of Histoplasma capsulatum organisms.
Authors:
Carol A. Kauffman
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Publication Detail:
Type:  JOURNAL ARTICLE    
Journal Detail:
Title:  Current infectious disease reports     Volume:  3     ISSN:  1534-3146     ISO Abbreviation:  Curr Infect Dis Rep     Publication Date:  2001 Jun 
Date Detail:
Created Date:  2001-May-31     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100888983     Medline TA:  Curr Infect Dis Rep     Country:  -    
Other Details:
Languages:  ENG     Pagination:  279-285     Citation Subset:  -    
Affiliation:
Division of Infectious Diseases, Veterans Affairs Healthcare System, 2215 Fuller Road, Ann Arbor, MI 48105. ckauff@umich.edu
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