Document Detail

A Pull-Back Algorithm to Determine the Unloaded Vascular Geometry in Anisotropic Hyperelastic AAA Passive Mechanics.
MedLine Citation:
PMID:  23192266     Owner:  NLM     Status:  Publisher    
Biomechanical studies on abdominal aortic aneurysms (AAA) seek to provide for better decision criteria to undergo surgical intervention for AAA repair. More accurate results can be obtained by using appropriate material models for the tissues along with accurate geometric models and more realistic boundary conditions for the lesion. However, patient-specific AAA models are generated from gated medical images in which the artery is under pressure. Therefore, identification of the AAA zero pressure geometry would allow for a more realistic estimate of the aneurysmal wall mechanics. This study proposes a novel iterative algorithm to find the zero pressure geometry of patient-specific AAA models. The methodology allows considering the anisotropic hyperelastic behavior of the aortic wall, its thickness and accounts for the presence of the intraluminal thrombus. Results on 12 patient-specific AAA geometric models indicate that the procedure is computational tractable and efficient, and preserves the global volume of the model. In addition, a comparison of the peak wall stress computed with the zero pressure and CT-based geometries during systole indicates that computations using CT-based geometric models underestimate the peak wall stress by 59 ± 64 and 47 ± 64 kPa for the isotropic and anisotropic material models of the arterial wall, respectively.
Fabián Riveros; Santanu Chandra; Ender A Finol; T Christian Gasser; Jose F Rodriguez
Related Documents :
24511336 - An efficient method of key-frame extraction based on a cluster algorithm.
24181216 - Acoustic intensity estimates from a solid rocket motor test firing.
23627966 - Scrub typhus islands in the taiwan area and the association between scrub typhus diseas...
24109736 - Cramér-rao bound for intravoxel incoherent motion diffusion weighted imaging fitting.
17539376 - A more accurate estimate of heritability.
12370006 - Recent progress in protein 3d structure comparison.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-29
Journal Detail:
Title:  Annals of biomedical engineering     Volume:  -     ISSN:  1521-6047     ISO Abbreviation:  Ann Biomed Eng     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0361512     Medline TA:  Ann Biomed Eng     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Mechanical Engineering Department/Aragon Institute of Engineering Research, Universidad de Zaragoza, Zaragoza, Spain.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Artery buckling: new phenotypes, models, and applications.
Next Document:  A molecular case report: functional assay of tyrosine kinase inhibitors in cells from a patient's pr...