Document Detail


Psyllium as therapeutic and drug delivery agent.
MedLine Citation:
PMID:  17329047     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
There is no doubt that fibers, in particular viscous dietary fibers, have positive effects on human health, both in the prevention and in treatment of chronic diseases. Dietary fibers from psyllium have been used extensively both as pharmacological supplements, food ingredients, in processed food to aid weight control, to regulation of glucose control for diabetic patients and reducing serum lipid levels in hyperlipidemics. Keeping in view, the pharmacological importance of psyllium polysaccharide and its gel-forming nature, this article discusses the therapeutic value of psyllium for the treatment of constipation, diarrhea, irritable bowel syndrome, inflammatory bowel disease-ulcerative colitis, colon cancer, diabetes and hypercholesterolemia and exploitation of psyllium for developing drug delivery systems.
Authors:
Baljit Singh
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Publication Detail:
Type:  Journal Article; Review     Date:  2007-01-21
Journal Detail:
Title:  International journal of pharmaceutics     Volume:  334     ISSN:  0378-5173     ISO Abbreviation:  Int J Pharm     Publication Date:  2007 Apr 
Date Detail:
Created Date:  2007-03-19     Completed Date:  2007-07-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7804127     Medline TA:  Int J Pharm     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  1-14     Citation Subset:  IM    
Affiliation:
Department of Chemistry, Himachal Pradesh University, Shimla 171005, India. baljitsinghhpu@yahoo.com
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MeSH Terms
Descriptor/Qualifier:
Cathartics / adverse effects,  therapeutic use*
Delayed-Action Preparations / chemistry*,  therapeutic use
Diabetes Mellitus / drug therapy
Dietary Fiber / therapeutic use
Drug Carriers / chemistry,  therapeutic use*
Drug Delivery Systems
Gastrointestinal Diseases / drug therapy
Humans
Hypercholesterolemia / drug therapy
Polymers / chemistry
Psyllium / adverse effects,  therapeutic use*
Chemical
Reg. No./Substance:
0/Cathartics; 0/Delayed-Action Preparations; 0/Drug Carriers; 0/Polymers; 8063-16-9/Psyllium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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