Document Detail

Psychotropics and sudden cardiac death.
MedLine Citation:
PMID:  23641438     Owner:  NLM     Status:  In-Data-Review    
Over the past two decades there has been a large increase in the number of patients prescribed psychotropic medications. Many of these agents are associated with QTc prolongation which is considered a marker for increased risk of sudden cardiac death due to malignant arrhythmias such as Torsades de pointes (TdP). Psychotropics rarely lead to sudden death in healthy individuals on a single QTc prolonging medication. However, factors such polypharmacy, recent initiation of a QTc prolonging medication, bradycardia, electrolyte abnormalities and preexisting arrhythmias increase the likelihood of psychotropic-induced sudden cardiac death. Therefore, clinicians must recognize which psychotropics and risk factors are associated with increased risk in order to minimize the risks of psychotropic QTc prolongation.
Jessica L Gören; Tuan Anh Dinh
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Publication Detail:
Type:  Journal Article     Date:  2013-03-01
Journal Detail:
Title:  Rhode Island medical journal (2013)     Volume:  96     ISSN:  0363-7913     ISO Abbreviation:  R I Med J (2013)     Publication Date:  2013  
Date Detail:
Created Date:  2013-05-03     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101605827     Medline TA:  R I Med J (2013)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  38-41     Citation Subset:  IM    
Associate Professor, Department of Pharmacy Practice, College of Pharmacy, University of Rhode Island; Instructor in Psychiatry, Harvard Medical School, Boston, MA; Senior Pharmacist Specialist, Cambridge Health Alliance.
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