Document Detail

Psychotropic and anticonvulsant drugs in subjects with autism: prevalence and patterns of use.
MedLine Citation:
PMID:  8543539     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To survey the prevalence and patterns of psychotropic and anticonvulsant medication and vitamin treatments in patients with autism. METHOD: Caregivers of 1,595 index cases were sent survey questionnaires by mail, and repeat questionnaires were sent twice if no reply was received. RESULTS: A total of 838 care providers (53%) responded to the survey. In all, 33.8% of the sample was taking some psychotropic drug or vitamin for autism or associated behavioral/psychiatric problems. A total of 19.2% reported having epilepsy, but only 13.2% were taking anticonvulsant drugs. More than 50% of the sample was taking some psychotropic, antiepileptic, vitamin, or "medical" agent. Of the agents taken, care providers were most satisfied with anticonvulsants, antidepressants, and stimulants. The use of each drug group was analyzed with respect to subject and demographic variables to evaluate medication patterns within this population. CONCLUSION: As in the often related clinical population of mental retardation, psychotropic medication appears to be heavily used in patients with autism.
M G Aman; M E Van Bourgondien; P L Wolford; G Sarphare
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of the American Academy of Child and Adolescent Psychiatry     Volume:  34     ISSN:  0890-8567     ISO Abbreviation:  J Am Acad Child Adolesc Psychiatry     Publication Date:  1995 Dec 
Date Detail:
Created Date:  1996-02-14     Completed Date:  1996-02-14     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8704565     Medline TA:  J Am Acad Child Adolesc Psychiatry     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1672-81     Citation Subset:  IM    
Nisonger Center, Ohio State University, Columbus 43210-1296, USA.
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MeSH Terms
Aged, 80 and over
Anticonvulsants / adverse effects,  therapeutic use*
Autistic Disorder / drug therapy*,  psychology
Child, Preschool
Drug Utilization
Middle Aged
North Carolina
Psychotropic Drugs / adverse effects,  therapeutic use*
Treatment Outcome
Grant Support
Reg. No./Substance:
0/Anticonvulsants; 0/Psychotropic Drugs

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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