Document Detail

Psychosocial stimuli and human plasma renin activity.
MedLine Citation:
PMID:  594285     Owner:  NLM     Status:  MEDLINE    
The effects of several types of acute psychosocial stimuli on plasma renin activity (PRA) were studied in normotensive healthy subjects. Puzzle-solving produced an increase in blood pressure but no significant change in PRA, although two of seven subjects did respond with large increases in PRA. Watching a disturbing movie also raised blood pressure, but did not alter PRA. In contrast, a combination of novelty, fear, and/or anticipation did constitute a significant stimulus for renin secretion; this was evidenced by the fact that naive subjects (who were not told in advance what to expect) had significantly higher PRAs on the first day of the 2-day puzzle-solving study. PRA on this day correlated strongly with anxiety proneness, as did the decrease from day 1 to day 2. We conclude that meaningful psychosocial stimuli can enhance renin secretion in susceptible individuals.
D M Clamage; A J Vander; D R Mouw
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Psychosomatic medicine     Volume:  39     ISSN:  0033-3174     ISO Abbreviation:  Psychosom Med     Publication Date:    1977 Nov-Dec
Date Detail:
Created Date:  1978-02-18     Completed Date:  1978-02-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0376505     Medline TA:  Psychosom Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  393-401     Citation Subset:  IM    
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MeSH Terms
Anxiety / etiology
Arousal / physiology
Blood Pressure
Cognition / physiology
Emotions / physiology
Problem Solving / physiology
Renin / blood*
Stress, Psychological*
Visual Perception
Reg. No./Substance:

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