Document Detail

Psychoneuroimmunologic effects of Ayurvedic oil-dripping treatment.
MedLine Citation:
PMID:  19123874     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: This study assessed the psychoneuroimmunologic changes achieved by Shirodhara, an Ayurvedic treatment, characterized by dripping oil on the forehead, in a randomized, controlled protocol involving a novel approach using a robotic system. METHODS: In the first experiment for the determination of the most appropriate conditions of Shirodhara, 16 healthy females (33 +/- 9 years old) underwent a 30-minute treatment. In the second study, another 16 healthy females (39 +/- 9 years old) were assigned to either the Shirodhara treatment or control supine position for 30 minutes, with monitoring of physiologic, biochemical, immunologic, and psychometric parameters including anxiety and altered states of consciousness (ASC). RESULTS: The subjects receiving Shirodhara treatment showed lowered levels of state anxiety and higher levels of ASC than those in the control position. Plasma noradrenaline and urinary serotonin excretion decreased significantly more after Shirodhara treatment than in the control. Plasma levels of thyrotropin-releasing hormone, dopamine, and natural killer (NK) cell activity were different between control and Shirodhara treatment. The correlation between anxiolysis and the depth of ASC was significant in the Shirodhara treatment group (r = 0.52, p < 0.05, N = 16), while in the control no correlation was obtained (r = 0.13, p = 0.64, N = 16). The increase in foot skin temperature after Shirodhara showed a significant correlation with anxiolysis and the depth of Trance of ASC (r = 0.58, p < 0.01, r = 0.43, p < 0.01, respectively). NK cell activity after Shirodhara treatment showed a significant correlation with anxiolysis and the depth of Trance of ASC (r = 0.33, p < 0.05, r = 0.56, p < 0.01, respectively). CONCLUSIONS: These results indicate that Shirodhara has anxiolytic and ASC-inducing effects, and it promotes a decrease of noradrenaline and exhibits a sympatholytic effect, resulting in the activation of peripheral foot skin circulation and immunopotentiation.
Kazuo Uebaba; Feng-Hao Xu; Hiroko Ogawa; Takashi Tatsuse; Bing-Hong Wang; Tatsuya Hisajima; Sonia Venkatraman
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Journal of alternative and complementary medicine (New York, N.Y.)     Volume:  14     ISSN:  1557-7708     ISO Abbreviation:  J Altern Complement Med     Publication Date:  2008 Dec 
Date Detail:
Created Date:  2009-01-06     Completed Date:  2009-04-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9508124     Medline TA:  J Altern Complement Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1189-98     Citation Subset:  IM    
Department of Presymptomatic Health Promotion, Institute of Natural Medicine, University of Toyama, Toyama, Japan.
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MeSH Terms
Analysis of Variance
Anxiety / therapy
Health Status
Killer Cells, Natural / metabolism
Medicine, Ayurvedic*
Neuroimmunomodulation / drug effects,  physiology*
Norepinephrine / blood
Oils, Volatile / administration & dosage*
Reference Values
Serotonin / urine
Therapy, Computer-Assisted / methods
Young Adult
Reg. No./Substance:
0/Oils, Volatile; 50-67-9/Serotonin; 51-41-2/Norepinephrine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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