Document Detail


Psychometric validation of a constipation symptom assessment questionnaire.
MedLine Citation:
PMID:  10522604     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Clinical management of constipation is complicated by the lack of a gold standard for evaluation of symptoms. A constipation symptom assessment instrument, the PAC-SYM, was developed to address the patient perspective on the disorder. Instrument content was based on literature review and results of focus groups. METHODS: Two hundred and sixteen patients at nine sites participated in a 6-week psychometric evaluation of the PAC-SYM. The final instrument contained 12 items assigned to 3 subscales: stool symptoms, rectal symptoms, and abdominal symptoms. The psychometric properties of this final instrument were assessed. RESULTS: Internal consistency and test-retest reliability of the final instrument was high (Cronbach's alpha = 0.89; intraclass correlation = 0.75). Concurrent validity was supported by the correlation with both subject and investigator constipation severity ratings (r= 0.68 and 0.72, respectively; P < 0.0001). Scores were moderately correlated with instruments measuring quality of life. Comparison of treatment responders with nonresponders showed the ability of the instrument to differentiate between groups on the basis of clinical severity (t = -6.12, P < 0.0001 ). Scores changed significantly over time among responders, indicating instrument responsiveness. CONCLUSIONS: The PAC-SYM is internally consistent, reproducible under stable conditions, valid, and responsive to change and provides a comprehensive means to assess the effectiveness of treatment for constipation.
Authors:
L Frank; L Kleinman; C Farup; L Taylor; P Miner
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Scandinavian journal of gastroenterology     Volume:  34     ISSN:  0036-5521     ISO Abbreviation:  Scand. J. Gastroenterol.     Publication Date:  1999 Sep 
Date Detail:
Created Date:  1999-11-10     Completed Date:  1999-11-10     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0060105     Medline TA:  Scand J Gastroenterol     Country:  NORWAY    
Other Details:
Languages:  eng     Pagination:  870-7     Citation Subset:  IM    
Affiliation:
Center for Health Outcomes Research, MEDTAP International, Inc., and MEDTAP Systems, LLC, Bethesda, Maryland 20814, USA.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Chronic Disease
Constipation* / diagnosis,  therapy
Dietary Fiber / therapeutic use
Factor Analysis, Statistical
Female
Humans
Magnesium / therapeutic use
Male
Middle Aged
Psychometrics
Questionnaires*
Reproducibility of Results
Statistics, Nonparametric
Chemical
Reg. No./Substance:
7439-95-4/Magnesium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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