Document Detail

Psychological trauma associated with the World Trade Center attacks and its effect on pregnancy outcome.
MedLine Citation:
PMID:  16115284     Owner:  NLM     Status:  MEDLINE    
The destruction of the World Trade Center (WTC) on 11 September 2001 was a source of enormous psychological trauma that may have consequences for the health of pregnant women and their fetuses. In this report, we describe the impact of extreme trauma on the birth outcomes of women highly exposed to the WTC. We enrolled 187 women who were pregnant and living or working within close proximity to the WTC on 11 September. Among women with singleton pregnancies, 52 completed at least one psychological assessment prior to delivery. In adjusted multivariable models, both post-traumatic stress symptomatology (PTSS) and moderate depression were associated with longer gestational durations, although only PTSS was associated with decrements in infant head circumference at birth (beta=-0.07, SE=0.03, P=0.01). The impact of stress resulting from extreme trauma may be different from that which results from ordinary life experiences, particularly with respect to cortisol production. As prenatal PTSS was associated with decrements in head circumference, this may influence subsequent neurocognitive development. Long-term follow-up of infants exposed to extreme trauma in utero is needed to evaluate the persistence of these effects.
Stephanie Mulherin Engel; Gertrud S Berkowitz; Mary S Wolff; Rachel Yehuda
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Paediatric and perinatal epidemiology     Volume:  19     ISSN:  0269-5022     ISO Abbreviation:  Paediatr Perinat Epidemiol     Publication Date:  2005 Sep 
Date Detail:
Created Date:  2005-08-23     Completed Date:  2005-10-25     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8709766     Medline TA:  Paediatr Perinat Epidemiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  334-41     Citation Subset:  IM    
Department of Community and Preventive Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA.
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MeSH Terms
Anxiety / psychology
Birth Weight
Depression / etiology,  psychology*
Gestational Age
Head / anatomy & histology
Infant, Newborn
Maternal Age
Pregnancy Complications / psychology*
Pregnancy Outcome / psychology*
September 11 Terrorist Attacks*
Stress Disorders, Post-Traumatic / etiology,  psychology*
Grant Support
5 R01 MH64675-03/MH/NIMH NIH HHS; P42 ES07384/ES/NIEHS NIH HHS

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