| Psychiatric and hostility factors related to use of anabolic steroids in monozygotic twins. | |
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MedLine Citation:
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PMID: 16529916 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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INTRODUCTION: Anabolic androgenic steroids (AAS) are derived by chemical manipulation of the testosterone molecule. The specified category of drugs produces anabolic, androgenic and psycho-active effects including elevated aggressive, hostile, violent and anti social behavior. OBJECTIVE: The objective of this case report observational study was to evaluate the possible psychological consequences of AS use in the twin user of each pair, compared with the non-user twin. METHODOLOGY: We studied two pairs of male monozygotic twins: one pair 24 years old and the other 31 years old, with absolute genome and phenotype similarity. One of the twins of each pair used AAS while the other did not. Both pairs lived in Hellenic provincial towns and followed a common training and nutrition regime. The psychometric instruments used were the Symptoms Check List-90 (SCL-90) and the Hostility and Direction of Hostility Questionnaire (HDHQ). The psychometric evaluations took place within a time interval of 6 months. RESULTS: The study found high levels of aggressiveness, hostility, anxiety and paranoid ideation in the twins who used AS. The non-user twins showed no deviation from their initial status. CONCLUSION: The use of AAS induced several important psychiatric changes in monozygotic twins which were not present in the twin who did not use AAS. |
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Authors:
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Thomas A Pagonis; Nikiforos V Angelopoulos; George N Koukoulis; Christos S Hadjichristodoulou; Paraskevi N Toli |
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Publication Detail:
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Type: Comparative Study; Journal Article; Twin Study Date: 2006-03-10 |
Journal Detail:
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Title: European psychiatry : the journal of the Association of European Psychiatrists Volume: 21 ISSN: 0924-9338 ISO Abbreviation: Eur. Psychiatry Publication Date: 2006 Dec |
Date Detail:
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Created Date: 2006-12-12 Completed Date: 2007-02-23 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9111820 Medline TA: Eur Psychiatry Country: France |
Other Details:
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Languages: eng Pagination: 563-9 Citation Subset: IM |
Affiliation:
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Department of Psychiatry, Thessaly University Medical School, Panagouli 12, 41222 Larissa, Greece. tpsportmed@the.forthnet.gr |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aggression / drug effects, psychology Anabolic Agents / adverse effects* Anxiety / chemically induced, psychology Doping in Sports / methods, psychology*, statistics & numerical data Hostility* Humans Male Mental Disorders / chemically induced*, psychology* Paranoid Behavior / chemically induced, psychology Psychiatric Status Rating Scales Psychometrics / methods Questionnaires Steroids / adverse effects* Stress, Psychological / chemically induced, diagnosis, psychology Substance-Related Disorders / diagnosis, psychology* Time Factors Twins, Monozygotic / drug effects, psychology |
| Chemical | |
Reg. No./Substance:
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0/Anabolic Agents; 0/Steroids |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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