Document Detail


Psoriatic spondyloarthropathy in men and women: a clinical, radiographic, and HLA study.
MedLine Citation:
PMID:  1516294     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Psoriatic spondyloarthropathy as defined by the presence of inflammatory back pain and stiffness, sacroiliitis on physical examination, radiographic evidence of grade greater than or equal to 2 sacroiliitis, and classical or paramarginal syndesmophytes on spinal radiographs was identified in 82 women and 112 men followed at the Psoriatic Arthritis Clinic according to a standard protocol. A logistic regression analysis was performed to look for variables which discriminate between men and women with this condition. No differences in type of peripheral arthritis, degree of damage, or medication were noted between the two groups. However, there was some evidence for more advanced spondyloarthropathy in men. There were no differences in the frequency of HLA B27 or any of the psoriatic arthritis-related HLA antigens. Thus, there may be gender-related differences in the expression of psoriatic spondyloarthropathy, which are unrelated to HLA antigens.
Authors:
D D Gladman; B Brubacher; D Buskila; P Langevitz; V T Farewell
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Clinical and investigative medicine. Médecine clinique et experimentale     Volume:  15     ISSN:  0147-958X     ISO Abbreviation:  Clin Invest Med     Publication Date:  1992 Aug 
Date Detail:
Created Date:  1992-10-02     Completed Date:  1992-10-02     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7804071     Medline TA:  Clin Invest Med     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  371-5     Citation Subset:  IM    
Affiliation:
Psoriatic Arthritis Clinic, University of Toronto, Ontario.
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MeSH Terms
Descriptor/Qualifier:
Adult
Arthritis, Psoriatic* / immunology,  radiography
Female
HLA Antigens / analysis*
HLA-B27 Antigen / analysis
Humans
Male
Middle Aged
Sex Characteristics
Spondylitis* / immunology,  radiography
Chemical
Reg. No./Substance:
0/HLA Antigens; 0/HLA-B27 Antigen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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